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Daniel Mittli

Explore the profile of Daniel Mittli including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 39
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Recent Articles
1.
Tukacs V, Mittli D, Hunyadi-Gulyas E, Darula Z, Juhasz G, Kardos J, et al.
Fluids Barriers CNS . 2024 Jan; 21(1):6. PMID: 38212833
Background: The brain extracellular fluid (ECF), composed of secreted neurotransmitters, metabolites, peptides, and proteins, may reflect brain processes. Analysis of brain ECF may provide new potential markers for synaptic activity...
2.
Mittli D
Brain Behav Immun Health . 2023 Nov; 34:100703. PMID: 38033612
Peripheral immune challenge induces neurobiological alterations in the brain and related neuropsychiatric symptoms both in humans and other mammals. One of the best known physiological effects of systemic inflammation is...
3.
Tukacs V, Mittli D, Hunyadi-Gulyas E, Hlatky D, Medzihradszky K, Darula Z, et al.
Mol Neurobiol . 2023 Feb; 60(6):3158-3174. PMID: 36808604
Declining cerebral blood flow leads to chronic cerebral hypoperfusion which can induce neurodegenerative disorders, such as vascular dementia. The reduced energy supply of the brain impairs mitochondrial functions that could...
4.
Mittli D, Tukacs V, Ravasz L, Csosz E, Kozma T, Kardos J, et al.
Brain Behav Immun Health . 2023 Jan; 28:100594. PMID: 36713475
Neuroinflammation induced by peripheral infections leads to various neuropsychiatric symptoms both in humans and laboratory animals, e.g., to the manifestation of sickness behavior that resembles some features of clinical depression....
5.
Toth V, Vadaszi H, Ravasz L, Mittli D, Matyas D, Molnar T, et al.
Cell Mol Life Sci . 2022 Aug; 79(9):471. PMID: 35932293
In synapses that show signs of local apoptosis and mitochondrial stress and undergo neuro-immunological synapse pruning, an increase in the levels of the presynaptic protein, neuronal-specific septin-3 can be observed....
6.
Szedlacsek H, Bajusz D, Badea R, Pop A, Bica C, Ravasz L, et al.
J Med Chem . 2021 Dec; 65(1):217-233. PMID: 34962802
Cognitive impairment and learning ability of the brain are directly linked to synaptic plasticity as measured in changes of long-term potentiation (LTP) and long-term depression (LTD) in animal models of...
7.
Mittli D, Tukacs V, Micsonai A, Ravasz L, Kardos J, Juhasz G, et al.
Front Immunol . 2021 Nov; 12:749433. PMID: 34759929
The investigation of the molecular background of direct communication of neurons and immune cells in the brain is an important issue for understanding physiological and pathological processes in the nervous...
8.
Tukacs V, Mittli D, Gyorffy B, Hunyady-Gulyas E, Hlatky D, Toth V, et al.
Sci Rep . 2020 Sep; 10(1):15999. PMID: 32994510
During chronic cerebral hypoperfusion (CCH), the cerebral blood flow gradually decreases, leading to cognitive impairments and neurodegenerative disorders, such as vascular dementia. The reduced oxygenation, energy supply induced metabolic changes,...
9.
Ravasz L, Kekesi K, Mittli D, Todorov M, Borhegyi Z, Ercsey-Ravasz M, et al.
Cereb Cortex . 2020 Jul; 31(2):731-745. PMID: 32710103
The prefrontal cortex (PFC) plays a key role in higher order cognitive functions and psychiatric disorders such as autism, schizophrenia, and depression. In the PFC, the two major classes of...