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Daniel Levner

Explore the profile of Daniel Levner including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 475
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Recent Articles
1.
Levner D, Ewart L
Expert Opin Drug Discov . 2023 Sep; 18(12):1313-1320. PMID: 37700537
Introduction: Drug-induced liver injury (DILI) is a potentially lethal condition that heavily impacts the pharmaceutical industry, causing approximately 21% of drug withdrawals and 13% of clinical trial failures. Recent evidence...
2.
Ewart L, Apostolou A, Briggs S, Carman C, Chaff J, Heng A, et al.
Commun Med (Lond) . 2023 Feb; 3(1):16. PMID: 36732600
No abstract available.
3.
Ewart L, Apostolou A, Briggs S, Carman C, Chaff J, Heng A, et al.
Commun Med (Lond) . 2023 Jan; 3(1):7. PMID: 36635369
No abstract available.
4.
Ewart L, Apostolou A, Briggs S, Carman C, Chaff J, Heng A, et al.
Commun Med (Lond) . 2022 Dec; 2(1):154. PMID: 36473994
Background: Conventional preclinical models often miss drug toxicities, meaning the harm these drugs pose to humans is only realized in clinical trials or when they make it to market. This...
5.
Bachar N, Benbassat D, Brailovsky D, Eshel Y, Gluck D, Levner D, et al.
Am J Hematol . 2021 Jul; 96(10):1264-1274. PMID: 34264525
Hematology analyzers capable of performing complete blood count (CBC) have lagged in their prevalence at the point-of-care. Sight OLO (Sight Diagnostics, Israel) is a novel hematological platform which provides a...
6.
Novak R, Ingram M, Marquez S, Das D, Delahanty A, Herland A, et al.
Nat Biomed Eng . 2020 Jan; 4(4):407-420. PMID: 31988458
Organ chips can recapitulate organ-level (patho)physiology, yet pharmacokinetic and pharmacodynamic analyses require multi-organ systems linked by vascular perfusion. Here, we describe an 'interrogator' that employs liquid-handling robotics, custom software and...
7.
Odijk M, van der Meer A, Levner D, Kim H, van der Helm M, Segerink L, et al.
Lab Chip . 2014 Nov; 15(3):745-52. PMID: 25427650
Trans-epithelial electrical resistance (TEER) measurements are widely used as real-time, non-destructive, and label-free measurements of epithelial and endothelial barrier function. TEER measurements are ideal for characterizing tissue barrier function in...
8.
Amir Y, Ben-Ishay E, Levner D, Ittah S, Abu-Horowitz A, Bachelet I
Nat Nanotechnol . 2014 Apr; 9(5):353-357. PMID: 24705510
Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines...
9.
Mali P, Aach J, Lee J, Levner D, Nip L, Church G
Nat Methods . 2013 Mar; 10(5):403-6. PMID: 23503053
We report an approach to barcode cells through cell-surface expression of programmable zinc-finger DNA-binding domains (surface zinc fingers, sZFs). We show that sZFs enable sequence-specific labeling of living cells by...
10.
Lin C, Jungmann R, Leifer A, Li C, Levner D, Church G, et al.
Nat Chem . 2012 Sep; 4(10):832-9. PMID: 23000997
The identification and differentiation of a large number of distinct molecular species with high temporal and spatial resolution is a major challenge in biomedical science. Fluorescence microscopy is a powerful...