Daniel L Kaufman
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Explore the profile of Daniel L Kaufman including associated specialties, affiliations and a list of published articles.
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42
Citations
807
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Recent Articles
1.
Tian J, Kaufman D
Biomedicines
. 2023 Feb;
11(2).
PMID: 36830790
GABA and GABA-receptors (GABA-Rs) play major roles in neurodevelopment and neurotransmission in the central nervous system (CNS). There has been a growing appreciation that GABA-Rs are also present on most...
2.
Tian J, Dillion B, Henley J, Comai L, Kaufman D
Front Immunol
. 2022 Nov;
13:1007955.
PMID: 36389819
Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate and adaptive immune system and act...
3.
Tian J, Song M, Kaufman D
Cells
. 2022 Apr;
11(7).
PMID: 35406645
We have proposed that antigen-specific immunotherapies (ASIs) for autoimmune diseases could be enhanced by administering target cell antigen epitopes (determinants) that are immunogenic but ignored by autoreactive T cells because...
4.
Song M, Tian J, Middleton B, Nguyen C, Kaufman D
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052808
Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic infiltrates in the salivary and lachrymal glands resulting in oral and ocular dryness. There are no clinically approved therapies...
5.
6.
Tian J, Middleton B, Kaufman D
Viruses
. 2021 Jun;
13(6).
PMID: 34071034
There is an urgent need for new approaches to limit the severity of coronavirus infections. Many cells of the immune system express receptors for the neurotransmitter γ-aminobutyric acid (GABA), and...
7.
Tian J, Song M, Kaufman D
Sci Rep
. 2021 Mar;
11(1):5402.
PMID: 33686135
Most multiple sclerosis (MS) patients given currently available disease-modifying drugs (DMDs) experience progressive disability. Accordingly, there is a need for new treatments that can limit the generation of new waves...
8.
Tian J, Middleton B, Lee V, Park H, Zhang Z, Kim B, et al.
Biomedicines
. 2021 Jan;
9(1).
PMID: 33418884
Some immune system cells express type A and/or type B γ-aminobutyric acid receptors (GABA-Rs and/or GABA-Rs). Treatment with GABA, which activates both GABA-Rs and GABA-Rs), and/or a GABA-R-specific agonist inhibits...
9.
Tian J, Middleton B, Kaufman D
bioRxiv
. 2020 Oct;
PMID: 33024975
There is an urgent need for new treatments to prevent and ameliorate severe illness and death induced by SARS-CoV-2 infection in COVID-19 patients. The coronavirus mouse hepatitis virus (MHV)-1 causes...
10.
Tian J, Dang H, OLaco K, Song M, Tiu B, Gilles S, et al.
Immunohorizons
. 2019 Oct;
3(10):498-510.
PMID: 31636084
Immune cells express γ-aminobutyric acid receptors (GABA-R), and GABA administration can inhibit effector T cell responses in models of autoimmune disease. The pharmacokinetic properties of GABA, however, may be suboptimal...