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Daniel Kornitzer

Explore the profile of Daniel Kornitzer including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 1004
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Recent Articles
1.
Pinsky M, Kornitzer D
J Fungi (Basel) . 2024 Jan; 10(1). PMID: 38276029
is a major human pathogenic fungus that is distinguished by its capability to switch from a yeast to a hyphal morphology under different conditions. Here, we analyze the cellular effects...
2.
Roy U, Yaish S, Weissman Z, Pinsky M, Dey S, Horev G, et al.
Elife . 2022 Oct; 11. PMID: 36200752
Heme can serve as iron source in many environments, including the iron-poor animal host environment. The fungal pathobiont expresses a family of extracellular CFEM hemophores that capture heme from host...
3.
Andrawes N, Weissman Z, Pinsky M, Moshe S, Berman J, Kornitzer D
PLoS Genet . 2022 Sep; 18(9):e1010390. PMID: 36084128
Heme (iron-protoporphyrin IX) is an essential but potentially toxic cellular cofactor. While most organisms are heme prototrophs, many microorganisms can utilize environmental heme as iron source. The pathogenic yeast Candida...
4.
Halder L, Babych S, Palme D, Mansouri-Ghahnavieh E, Ivanov L, Ashonibare V, et al.
mBio . 2022 Feb; 13(1):e0356321. PMID: 35132877
In response to infections, human immune cells release extracellular vesicles (EVs) that carry a situationally adapted cocktail of proteins and nucleic acids, including microRNAs (miRNAs), to coordinate the immune response....
5.
Weissman Z, Pinsky M, Donegan R, Reddi A, Kornitzer D
Cell Microbiol . 2020 Oct; 23(2):e13282. PMID: 33104284
Candida albicans is a major fungal pathogen that can utilise hemin and haemoglobin as iron sources in the iron-scarce host environment. While C. albicans is a heme prototroph, we show...
6.
Kornitzer D, Roy U
Biochim Biophys Acta Mol Cell Res . 2020 Aug; 1867(11):118817. PMID: 32777371
Iron acquisition is challenging in most environments. As an alternative to elemental iron, organisms can take up iron-protoporphyrin IX, or heme. Heme can be found in decaying organic matter and...
7.
Pinsky M, Roy U, Moshe S, Weissman Z, Kornitzer D
mBio . 2020 Apr; 11(2). PMID: 32317324
A large portion of biological iron is found in the form of an iron-protoporphyrin IX complex, or heme. In the human host environment, which is exceptionally poor in free iron,...
8.
Weissman Z, Pinsky M, Wolfgeher D, Kron S, Truman A, Kornitzer D
Biochim Biophys Acta Proteins Proteom . 2020 Jan; 1868(3):140135. PMID: 31964485
Heat shock proteins are best known for their role as chaperonins involved in general proteostasis, but they can also participate in specific cellular regulatory pathways, e.g. via their post-translational modification....
9.
Roy U, Kornitzer D
Curr Opin Microbiol . 2019 Jul; 52:77-83. PMID: 31265986
Heme is a bioavailable source of iron, for which different fungi have evolved several distinct acquisition mechanisms. In the iron-scarce animal host, in particular, microbial pathogens are able to utilize...
10.
Kornitzer D
J Fungi (Basel) . 2019 Mar; 5(1). PMID: 30823468
is a human commensal fungus that is able to assume several morphologies, including yeast, hyphal, and pseudohyphal. Under a range of conditions, performs a regulated switch to the filamentous morphology,...