Daniel K West
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Explore the profile of Daniel K West including associated specialties, affiliations and a list of published articles.
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6
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73
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Recent Articles
1.
ONeill S, Rubinstein W, Sener S, Weissman S, Newlin A, West D, et al.
Breast Cancer Res Treat
. 2008 Jul;
115(2):365-71.
PMID: 18661230
Purpose: To address the widespread concern that false-positive results during breast MRI screening may have adverse psychological effects. Methods: Impact of Event Scale measurements in 103 high-risk women enrolled in...
2.
West D, Paci E, Olmsted P
Phys Rev E Stat Nonlin Soft Matter Phys
. 2007 Feb;
74(6 Pt 1):061912.
PMID: 17280101
Mechanical unfolding of polyproteins by force spectroscopy provides valuable insight into their free energy landscapes. Most experiments of the unfolding process have been fit to two-state and/or one dimensional models,...
3.
West D, Olmsted P, Paci E
J Chem Phys
. 2006 Dec;
125(20):204910.
PMID: 17144743
The equilibrium free energy difference between two long-lived molecular species or "conformational states" of a protein (or any other molecule) can in principle be estimated by measuring the work needed...
4.
West D, Brockwell D, Paci E
Biophys J
. 2006 Jul;
91(5):L51-3.
PMID: 16815903
Proteins are actively unfolded to pass through narrow channels in macromolecular complexes that catalyze protein translocation and degradation. Catalyzed unfolding shares many features that characterize the mechanical unfolding of proteins...
5.
West D, Olmsted P, Paci E
J Chem Phys
. 2006 May;
124(15):154909.
PMID: 16674267
Single-molecule experiments and their application to probe the mechanical resistance and related properties of proteins provide a new dimension in our knowledge of these important and complex biological molecules. Single-molecule...
6.
West D, Brockwell D, Olmsted P, Radford S, Paci E
Biophys J
. 2005 Oct;
90(1):287-97.
PMID: 16214858
Recent experiments have demonstrated that proteins unfold when two atoms are mechanically pulled apart, and that this process is different to when heated or when a chemical denaturant is added...