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Daniel J Toft

Explore the profile of Daniel J Toft including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 308
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Recent Articles
1.
Toft D, Schneider A
Thyroid . 2022 Apr; 32(6):607-610. PMID: 35469429
No abstract available.
2.
Moyer T, Chen F, Toft D, Ruff Y, Cryns V, Stupp S
ACS Biomater Sci Eng . 2020 Dec; 5(11):6046-6053. PMID: 33304996
The development of tumor-targeted nanoscale carriers for the delivery of cancer therapeutics offers the ability to increase efficacy while limiting off-target toxicity. In this work we focused on targeting death...
3.
Leung A, Bauer A, Benvenga S, Brenner A, Hennessey J, Hurley J, et al.
Thyroid . 2017 May; 27(7):865-877. PMID: 28537500
This document serves to summarize the issues and the American Thyroid Association (ATA) position regarding the use of potassium iodide as a thyroid blocking agent in the event of a...
4.
Toft D, Fuller M, Schipma M, Chen F, Cryns V, Layden B
Genom Data . 2016 Jun; 9:10-7. PMID: 27330996
Emerging evidence suggests molecular chaperones have a role in the pathogenesis of obesity and diabetes. As αB-crystallin and HspB2 are molecular chaperones and data suggests their expression is elevated in...
5.
Moyer T, Finbloom J, Chen F, Toft D, Cryns V, Stupp S
J Am Chem Soc . 2014 Oct; 136(42):14746-52. PMID: 25310840
Supramolecular self-assembly offers promising new ways to control nanostructure morphology and respond to external stimuli. A pH-sensitive self-assembled system was developed to both control nanostructure shape and respond to the...
6.
Toft D, Moyer T, Standley S, Ruff Y, Ugolkov A, Stupp S, et al.
ACS Nano . 2012 Aug; 6(9):7956-65. PMID: 22928955
Self-assembled peptide amphiphiles (PAs) consisting of hydrophobic, hydvrogen-bonding, and charged hydrophilic domains form cylindrical nanofibers in physiological conditions and allow for the presentation of a high density of bioactive epitopes...
7.
Soukasene S, Toft D, Moyer T, Lu H, Lee H, Standley S, et al.
ACS Nano . 2011 Nov; 5(11):9113-21. PMID: 22044255
Self-assembling peptide amphiphile (PA) nanofibers were used to encapsulate camptothecin (CPT), a naturally occurring hydrophobic chemotherapy agent, using a solvent evaporation technique. Encapsulation by PA nanofibers was found to improve...
8.
Toft D, Cryns V
Mol Endocrinol . 2010 Sep; 25(2):199-211. PMID: 20861225
The classification of breast cancer into molecular subtypes with distinctive gene expression signatures that predict treatment response and prognosis has ushered in a new era of personalized medicine for this...
9.
Standley S, Toft D, Cheng H, Soukasene S, Chen J, Raja S, et al.
Cancer Res . 2010 Apr; 70(8):3020-6. PMID: 20354185
Nanotechnology offers novel delivery vehicles for cancer therapeutics. Potential advantages of nanoscale platforms include improved pharmacokinetics, encapsulation of cytotoxic agents, enhanced accumulation of therapeutics in the tumor microenvironment, and improved...
10.
Layden B, Dubner S, Toft D, Kopp P, Grimm S, Molitch M
Pituitary . 2009 Jan; 14(2):194-7. PMID: 19123039
We present an unusual case of primary central nervous system (CNS) lymphoma presenting with bilateral symmetric hypothalamic lesions causing diabetes insipidus and hypopituitarism. A 50-year-old male presented initially with mental...