Daniel Goncalves-Carneiro
Overview
Explore the profile of Daniel Goncalves-Carneiro including associated specialties, affiliations and a list of published articles.
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16
Citations
479
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Recent Articles
1.
Barton R, Tregoning J, Wang Z, Goncalves-Carneiro D, Patel R, McKay P, et al.
Mol Ther Nucleic Acids
. 2025 Jan;
36(1):102400.
PMID: 39759876
Self-amplifying RNA (saRNA) is an extremely promising platform because it can produce more protein for less RNA. We used a sort and sequence approach to identify host cell factors associated...
2.
Bohn J, Meagher J, Takata M, Goncalves-Carneiro D, Yeoh Z, Ohi M, et al.
Nat Commun
. 2024 Dec;
15(1):10834.
PMID: 39738020
ZAP is an antiviral protein that binds to and depletes viral RNA, which is often distinguished from vertebrate host RNA by its elevated CpG content. Two ZAP cofactors, TRIM25 and...
3.
Francesco Rodrigues de Oliveira B, Donovan-Banfield I, Penrice-Randal R, Casey R, Goncalves-Carneiro D
Microbiology (Reading)
. 2024 Jun;
170(6).
PMID: 38860877
The past decade has seen growing awareness of the challenges faced by LGBTQIA+ scientists, including discrimination in the workplace and the lack of representation. Initiatives such as 500 Queer Scientists,...
4.
Lo R, Goncalves-Carneiro D
Biosci Rep
. 2023 Aug;
43(9).
PMID: 37606964
Nucleotide composition plays a crucial role in the structure, function and recognition of RNA molecules. During infection, virus RNA is exposed to multiple endogenous proteins that detect local or global...
5.
Lei X, Goncalves-Carneiro D, Zang T, Bieniasz P
Elife
. 2023 Jan;
12.
PMID: 36688533
The encapsidation of HIV-1 gRNA into virions is enabled by the binding of the nucleocapsid (NC) domain of the HIV-1 Gag polyprotein to the structured viral RNA packaging signal (Ψ)...
6.
Goncalves-Carneiro D, Mastrocola E, Lei X, DaSilva J, Chan Y, Bieniasz P
Nat Microbiol
. 2022 Sep;
7(10):1558-1567.
PMID: 36075961
Attenuation of a virulent virus is a proven approach for generating vaccines but can be unpredictable. For example, synonymous recoding of viral genomes can attenuate replication but sometimes results in...
7.
Xue G, Braczyk K, Goncalves-Carneiro D, Dawidziak D, Sanchez K, Ong H, et al.
PLoS Pathog
. 2022 Feb;
18(2):e1009202.
PMID: 35130321
Zinc-finger antiviral protein (ZAP), also known as poly(ADP-ribose) polymerase 13 (PARP13), is an antiviral factor that selectively targets viral RNA for degradation. ZAP is active against both DNA and RNA...
8.
Goncalves-Carneiro D, Takata M, Ong H, Shilton A, Bieniasz P
PLoS Pathog
. 2021 Apr;
17(4):e1009545.
PMID: 33901262
The human zinc finger antiviral protein (ZAP) recognizes RNA by binding to CpG dinucleotides. Mammalian transcriptomes are CpG-poor, and ZAP may have evolved to exploit this feature to specifically target...
9.
Goncalves-Carneiro D, Bieniasz P
mBio
. 2021 Jan;
12(1).
PMID: 33402534
The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research...
10.
Fletcher N, Meredith L, Tidswell E, Bryden S, Goncalves-Carneiro D, Chaudhry Y, et al.
J Gen Virol
. 2020 Jul;
101(10):1090-1102.
PMID: 32692647
Some free fatty acids derived from milk and vegetable oils are known to have potent antiviral and antibacterial properties. However, therapeutic applications of short- to medium-chain fatty acids are limited...