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Daniel G Baden

Explore the profile of Daniel G Baden including associated specialties, affiliations and a list of published articles. Areas
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Articles 66
Citations 1336
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Recent Articles
1.
Finol-Urdaneta R, Zhorov B, Baden D, Adams D
Mar Drugs . 2023 Jul; 21(7). PMID: 37504927
Brevetoxins (PbTx) and brevenal are marine ladder-frame polyethers. PbTx binds to and activates voltage-gated sodium (Nav) channels in native tissues, whereas brevenal antagonizes these actions. However, the effects of PbTx...
2.
Saha T, Aoun J, Sarkar P, Bourdelais A, Baden D, Leblanc N, et al.
Pharm Biol . 2021 Aug; 59(1):1008-1015. PMID: 34362288
Context: Cucumber ( Linn. [Cucurbitaceae]) is widely known for its purgative, antidiabetic, antioxidant, and anticancer therapeutic potential. However, its effect on gastrointestinal (GI) disease is unrecognised. Objective: This study investigated...
3.
Sequeira E, Pierce M, Akasheh D, Sellers S, Gerwick W, Baden D, et al.
Mar Drugs . 2020 Jul; 18(7). PMID: 32708077
Emerging literature suggests that after a stroke, the peri-infarct region exhibits dynamic changes in excitability. In rodent stroke models, treatments that enhance excitability in the peri-infarct cerebral cortex promote motor...
4.
Konoki K, Baden D, Scheuer T, Catterall W
Toxins (Basel) . 2019 Sep; 11(9). PMID: 31484365
Brevetoxins are produced by dinoflagellates such as in warm-water red tides and cause neurotoxic shellfish poisoning. They bind to voltage-gated sodium channels at neurotoxin receptor 5, making the channels more...
5.
Hardison D, Holland W, McCall J, Bourdelais A, Baden D, Darius H, et al.
PLoS One . 2016 Apr; 11(4):e0153348. PMID: 27073998
Ciguatera fish poisoning is an illness suffered by > 50,000 people yearly after consumption of fish containing ciguatoxins (CTXs). One of the current methodologies to detect ciguatoxins in fish is...
6.
Fleming L, Backer L, Kirkpatrick B, Clark R, Dalpra D, Johnson D, et al.
Harmful Algae 2002 (2002) . 2015 Oct; 10:508-510. PMID: 26436145
Very little has been published in the scientific literature on the human health effects of Florida red tide, either as human clinical case reports or formal epidemiologic studies. In addition...
7.
Dickey R, Plakas S, Jester E, El Said K, Johannessen J, Flewelling L, et al.
Harmful Algae 2002 (2002) . 2015 Oct; 10:300-302. PMID: 26436143
A thirteen-laboratory comparative study tested the performance of four methods as alternatives to mouse bioassay for the determination of brevetoxins in shellfish. The methods were N2a neuroblastoma cell assay, two...
8.
Naar J, Weidner A, Baden D
Harmful Algae 2002 (2002) . 2015 Oct; 10:291-293. PMID: 26436142
A competitive Enzyme-Linked Immuno-Sorbent Assay (competitive ELISA) has been developed for analyzing brevetoxins (PbTxs). Antibodies to brevetoxins were used in combination with a multi-step signal amplification procedure for the detection...
9.
Hardman R, Cooper W, Bourdelais A, Gardinali P, Baden D
Harmful Algae 2002 (2002) . 2015 Oct; 10:153-154. PMID: 26436141
We investigated the effects of solar radiation on brevetoxin (PbTx2). Our findings suggest that natural sunlight mediates brevetoxin (PbTx2) degradation and results in brevetoxin by-product formation via photochemical processes.
10.
McCall J, Goodman A, Jacocks H, Thompson A, Baden D, Bourdelais A
J Nat Prod . 2014 Sep; 77(9):2014-20. PMID: 25226846
The marine dinoflagellate Karenia brevis produces a family of neurotoxins known as brevetoxins. Brevetoxins elicit their effects by binding to and activating voltage-sensitive sodium channels (VSSCs) in cell membranes. K....