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Daniel Fernandes

Explore the profile of Daniel Fernandes including associated specialties, affiliations and a list of published articles. Areas
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Articles 89
Citations 3077
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Recent Articles
1.
Nakashima M, Delfrate G, Albino L, Alves G, Oliveira J, Fernandes D
Acute Crit Care . 2025 Feb; 40(1):46-58. PMID: 39978956
Background: Sepsis is a life-threatening condition that affects the cardiovascular and renal systems. Severe hypotension during sepsis compromises tissue perfusion, which can lead to multiple organ dysfunction and death. Phosphodiesterase...
2.
Baker M, Fernandes D, Figueredo C
J Clin Med . 2024 Dec; 13(23). PMID: 39685706
Identifying patients with a strong pro-inflammatory phenotype may allow clinicians to underpin high-risk individuals based on early inflammatory marker profiles and to personalize approaches to preventative treatments. The objective of...
3.
Alves G, Oliveira J, Nakashima M, Delfrate G, Sordi R, Assreuy J, et al.
Eur J Pharmacol . 2024 Sep; 983:177015. PMID: 39332796
Background: Phosphodiesterase-4 (PDE4) is responsible for terminating cyclic adenosine monophosphate (cAMP) signalling. PDE4 inhibitors, such as roflumilast (RFM), have anti-inflammatory activity and have been studied in inflammation-induced tissue damage in...
4.
Pisetta L, Tonin F, Akiyoshi F, Santos F, Fernandes D
Int J Qual Health Care . 2024 Aug; 36(3). PMID: 39215969
Adverse events (AEs), and particularly adverse drug events (ADEs), represent a health problem as they can cause permanent damage or death. Understanding the frequency, location, and causes of ADEs can...
5.
Alves G, Aimaretti E, da Silveira Hahmeyer M, Einaudi G, Porchietto E, Rubeo C, et al.
Biomed Pharmacother . 2024 Jul; 178:117191. PMID: 39079263
Casein kinase II (CK2) has recently emerged as a pivotal mediator in the propagation of inflammation across various diseases. Nevertheless, its role in the pathogenesis of sepsis remains unexplored. Here,...
6.
Uppuganti S, Creecy A, Fernandes D, Garrett K, Donovan K, Ahmed R, et al.
Calcif Tissue Int . 2024 Jul; 115(3):298-314. PMID: 39012489
Obesity and type 2 diabetes (T2D) are risk factors for fragility fractures. It is unknown whether this elevated risk is due to a diet favoring obesity or the diabetes that...
7.
Ragsdale M, Dow B, Fernandes D, Han Y, Parikh A, Boyapati K, et al.
Surgery . 2024 Jul; 176(4):1143-1147. PMID: 38997863
Background: Sentinel lymph node biopsy for melanoma determines treatment and prognostic factors and improves disease-specific survival. To risk-stratify patients for sentinel lymph node biopsy consideration, Memorial Sloan Kettering Cancer Center...
8.
Delfrate G, Albino L, Assreuy J, Fernandes D
Shock . 2024 Jun; 62(4):547-555. PMID: 38888572
Sepsis is a life-threatening condition widely studied by animal models. Cecal ligation and puncture (CLP) is still regarded as the gold standard model for sepsis. However, CLP has limitations due...
9.
Antonio M, Weiss C, Gao Z, Sawyer S, Oberreiter V, Moots H, et al.
Elife . 2024 Jan; 13. PMID: 38288729
Ancient DNA research in the past decade has revealed that European population structure changed dramatically in the prehistoric period (14,000-3000 years before present, YBP), reflecting the widespread introduction of Neolithic...
10.
Sordi R, Bojko L, Oliveira F, Rosales T, Souza C, Moreno L, et al.
Intensive Care Med Exp . 2024 Jan; 12(1):2. PMID: 38194181
Background: Hemorrhagic shock (HS), which causes insufficient tissue perfusion, can result in multiple organ failure (MOF) and death. This study aimed to evaluate whether doxycycline (DOX) protects cardiovascular, kidney, and...