Daniel D Myers Jr
Overview
Explore the profile of Daniel D Myers Jr including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
2121
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0
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Recent Articles
1.
Myers Jr D, Ning J, Lester P, Adili R, Hawley A, Durham L, et al.
J Vasc Surg Venous Lymphat Disord
. 2021 Apr;
10(1):211-220.
PMID: 33872819
Background: This study evaluated E-selectin inhibition with GMI-1271 (Uproleselan [GMI]) alone and in combination with the standard of care low-molecular-weight heparin (LMWH) to improve vein recanalization, decrease vein wall inflammation...
2.
Beninson J, Lofgren J, Lester P, Hileman M, Berkowitz D, Myers Jr D
J Am Assoc Lab Anim Sci
. 2018 May;
57(3):258-267.
PMID: 29784076
NSAID analgesics may confound models that require inflammation to mimic disease development in humans. This effect presents a challenge for veterinary staff and investigators, because surgery is often necessary to...
3.
Culmer D, Dunbar M, Hawley A, Sood S, Sigler R, Henke P, et al.
Thromb Haemost
. 2017 Mar;
117(6):1171-1181.
PMID: 28300869
Selectins, such as E-selectin (CD62E), function in venous thrombosis by binding and activating immune cells to initiate the coagulation cascade. GMI-1271 is a small molecule antagonist that inhibits E-selectin activity....
4.
Lester P, Coleman D, Diaz J, Jackson T, Hawley A, Mathues A, et al.
Arterioscler Thromb Vasc Biol
. 2017 Feb;
37(5):942-948.
PMID: 28232327
Objective: Warfarin is the current standard for oral anticoagulation therapy in patients with mechanical heart valves, yet optimal therapy to maximize anticoagulation and minimize bleeding complications requires routine coagulation monitoring,...
5.
Obi A, Stringer K, Diaz J, Finkel M, Farris D, Yeomans L, et al.
J Vasc Surg Venous Lymphat Disord
. 2016 Mar;
4(2):221-30.
PMID: 26993871
Objective: Age is a significant risk factor for the development of venous thrombosis (VT), but the mechanism(s) that underlie this risk remain(s) undefined and poorly understood. Aging is known to...
6.
Aziz F, Raffetto J, Diaz J, Myers Jr D, Ozsvath K, Carman T, et al.
Phlebology
. 2016 Jan;
32(1):19-26.
PMID: 26769720
Objectives Venous leg ulcers (VLU) are the most severe clinical sequelae of venous reflux and post thrombotic syndrome. There is a consensus that ablation of refluxing vein segments and treatment...
7.
Diaz J, Wrobleski S, Alvarado C, Hawley A, Doornbos N, Lester P, et al.
Arterioscler Thromb Vasc Biol
. 2015 Feb;
35(4):829-37.
PMID: 25657307
Objective: Aptamers are oligonucleotides targeting protein-protein interactions with pharmacokinetic profiles and activity reversal options. Although P-selectin and von Willebrand factor (vWF) have been implicated in the development of venous thrombosis...
8.
DeRoo E, Wrobleski S, Shea E, Al-Khalil R, Hawley A, Henke P, et al.
Blood
. 2014 Nov;
125(11):1813-21.
PMID: 25428218
Galectin-3-binding protein (gal3bp) and its receptor/ligand, galectin-3 (gal3), are secreted proteins that initiate signaling cascades in several diseases, and recent human proteomic data suggest they may play a role in...
9.
Hish Jr G, Diaz J, Hawley A, Myers Jr D, Lester P
J Am Assoc Lab Anim Sci
. 2014 Sep;
53(5):485-93.
PMID: 25255071
Venous thrombosis (VT) is a significant cause of morbidity and mortality in humans. Surgical animal models are crucial in studies investigating the pathogenesis of this disease and evaluating VT therapies....
10.
Shuster K, Wrobleski S, Hawley A, Lucchesi B, Sorenson D, Bergin I, et al.
Comp Med
. 2013 Jun;
63(3):244-51.
PMID: 23759527
The use of thrombolytic agents has greatly improved patient outcomes, but the prothrombotic response to these drugs in vivo is unknown. Approximately 24 h after we induced thrombosis in male...