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Daniel Christen

Explore the profile of Daniel Christen including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 131
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Recent Articles
1.
Christen D, Lauinger M, Brunner M, Dengjel J, Brummer T
Cell Commun Signal . 2024 Sep; 22(1):428. PMID: 39223665
BRAF serves as a gatekeeper of the RAS/RAF/MEK/ERK pathway, which plays a crucial role in homeostasis. Since aberrant signalling of this axis contributes to cancer and other diseases, it is...
2.
Picardi C, Caparrotti F, Montemurro M, Christen D, Schaub N, Fargier-Voiron M, et al.
Cancers (Basel) . 2024 Jul; 16(13). PMID: 39001380
Rectal cancer typically necessitates a combination of radiotherapy (RT), chemotherapy, and surgery. The associated functional disorders and reduction in quality of life have led to an increasing interest in organ...
3.
Lauinger M, Christen D, Klar R, Roubaty C, Heilig C, Stumpe M, et al.
Sci Adv . 2023 Sep; 9(35):eade7486. PMID: 37656784
In-frame exon 12 deletions are increasingly identified in various tumor types. The resultant BRAF oncoproteins usually lack five amino acids in the β3-αC helix linker and sometimes contain de novo...
4.
Langhammer M, Schopf J, Jaquet T, Horn K, Angel M, Spohr C, et al.
Leukemia . 2023 May; 37(7):1474-1484. PMID: 37161070
The persistence of leukemic stem cells (LSCs) represents a problem in the therapy of chronic myeloid leukemia (CML). Hence, it is of utmost importance to explore the underlying mechanisms to...
5.
Zhang Y, Yang Y, Saurer M, Schaub M, Gessler A, Lehmann M, et al.
Front Plant Sci . 2023 Mar; 14:1142595. PMID: 36909442
Many carbon-related physiological questions in plants such as carbon (C) limitation or starvation have not yet been resolved thoroughly due to the lack of suitable experimental methodology. As a first...
6.
Christen D, Killikelly C, Maercker A, Augsburger M
Clin Psychol Eur . 2022 Nov; 3(4):e5501. PMID: 36398291
Background: In the 11th revision of the International Classification of Diseases (ICD-11) posttraumatic stress disorder (PTSD) and the complex variant (CPTSD) were newly conceptualised. The International Trauma Questionnaire (ITQ) was...
7.
Gomez-Auli A, Hillebrand L, Christen D, Gunther S, Biniossek M, Peters C, et al.
Cell Mol Life Sci . 2020 May; 78(2):733-755. PMID: 32385587
Previous clinical and experimental evidence strongly supports a breast cancer-promoting function of the lysosomal protease cathepsin B. However, the cathepsin B-dependent molecular pathways are not completely understood. Here, we studied...
8.
Christen D
Praxis (Bern 1994) . 2019 Jan; 108(1):19-22. PMID: 30621538
Immunosuppression, Surgery, Complication? Abstract. Surgical conditions sometimes pose major diagnostic and therapeutic challenges for immunosuppressed patients. Especially in patients suffering from diseases with potential septic emergencies or postoperative complications, the...
9.
Christen D, Steffen R, Schlagenhauf P
Am J Trop Med Hyg . 2006 Dec; 75(6):1188-94. PMID: 17172391
Despite sophisticated intensive medicine, between one and three malaria-associated deaths occur annually in Switzerland. In this retrospective study, 33 deaths (25 men and 8 women) caused by falciparum malaria reported...
10.
Dincler S, Koller M, Steurer J, Bachmann L, Christen D, Buchmann P
Dis Colon Rectum . 2003 Oct; 46(10):1371-8. PMID: 14530677
Purpose: The number of operations to reach a plateau phase in colorectal laparoscopic surgery is still under debate. There are few publications reporting on multidimensional assessment of the learning curve,...