Danica M Sutherland
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Explore the profile of Danica M Sutherland including associated specialties, affiliations and a list of published articles.
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23
Citations
271
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Recent Articles
1.
Dermody T, Sutherland D
mBio
. 2025 Feb;
16(3):e0296424.
PMID: 39932305
Binding to cellular receptors initiates viral replication and dictates sites in the host infected by the virus. As illustrated by mammalian orthoreovirus (reovirus), viruses can bind several types of receptors...
2.
Dos Santos Natividade R, Dumitru A, Nicoli A, Strebl M, Sutherland D, Welsh O, et al.
Nanoscale Horiz
. 2024 Sep;
9(11):1925-1937.
PMID: 39347978
Understanding the mechanisms underlying viral entry is crucial for controlling viral diseases. In this study, we investigated the interactions between reovirus and Nogo-receptor 1 (NgR1), a key mediator of reovirus...
3.
Griswold K, Vasylieva I, Smith M, Fiske K, Welsh O, Roth A, et al.
mSphere
. 2024 Sep;
9(10):e0062924.
PMID: 39320067
Serotype 3 (T3) strains of mammalian orthoreovirus (reovirus) spread to the central nervous system to infect the brain and cause lethal encephalitis in newborn mice. Although reovirus targets several regions...
4.
Welsh O, Roth A, Sutherland D, Dermody T
J Virol
. 2024 Aug;
98(10):e0131424.
PMID: 39212451
No abstract available.
5.
Welsh O, Roth A, Sutherland D, Dermody T
J Virol
. 2024 May;
98(6):e0030524.
PMID: 38771042
Importance: Viral attachment proteins can serve multiple functions during viral replication, including attachment to host cells, cell entry and disassembly, and modulation of host immune responses. The relationship between viral...
6.
Shang P, Dos Santos Natividade R, Taylor G, Ray A, Welsh O, Fiske K, et al.
Cell Host Microbe
. 2024 May;
32(6):980-995.e9.
PMID: 38729153
Mammalian orthoreovirus (reovirus) is a nonenveloped virus that establishes primary infection in the intestine and disseminates to sites of secondary infection, including the CNS. Reovirus entry involves multiple engagement factors,...
7.
Sutherland D, Strebl M, Koehler M, Welsh O, Yu X, Hu L, et al.
Proc Natl Acad Sci U S A
. 2023 Jun;
120(24):e2219404120.
PMID: 37276413
Nogo-66 receptor 1 (NgR1) binds a variety of structurally dissimilar ligands in the adult central nervous system to inhibit axon extension. Disruption of ligand binding to NgR1 and subsequent signaling...
8.
Shang P, Simpson J, Taylor G, Sutherland D, Welsh O, Aravamudhan P, et al.
Nat Commun
. 2023 May;
14(1):2615.
PMID: 37147336
Mammalian orthoreovirus (reovirus) infects most mammals and is associated with celiac disease in humans. In mice, reovirus infects the intestine and disseminates systemically to cause serotype-specific patterns of disease in...
9.
Aravamudhan P, Guzman-Cardozo C, Urbanek K, Welsh O, Konopka-Anstadt J, Sutherland D, et al.
J Virol
. 2022 Mar;
96(8):e0005522.
PMID: 35353001
Engagement of host receptors is essential for viruses to enter target cells and initiate infection. Expression patterns of receptors in turn dictate host range, tissue tropism, and disease pathogenesis during...
10.
Lentscher A, McAllister N, Griswold K, Martin J, Welsh O, Sutherland D, et al.
J Infect Dis
. 2022 Feb;
227(3):457-465.
PMID: 35196388
Background: Chikungunya virus (CHIKV) is an arbovirus that periodically emerges to cause large epidemics of arthritic disease. Although the robust immunity elicited by live-attenuated virus (LAV) vaccine candidates makes them...