Dana Braff
Overview
Explore the profile of Dana Braff including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
1052
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0
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Recent Articles
1.
Lobritz M, Andrews I, Braff D, Porter C, Gutierrez A, Furuta Y, et al.
Cell Chem Biol
. 2022 Jan;
29(2):276-286.e4.
PMID: 34990601
β-Lactam antibiotics disrupt the assembly of peptidoglycan (PG) within the bacterial cell wall by inhibiting the enzymatic activity of penicillin-binding proteins (PBPs). It was recently shown that β-lactam treatment initializes...
2.
Takahashi M, Tan X, Dy A, Braff D, Akana R, Furuta Y, et al.
Nat Commun
. 2018 Aug;
9(1):3347.
PMID: 30131493
There is a need for large-scale, longitudinal studies to determine the mechanisms by which the gut microbiome and its interactions with the host affect human health and disease. Current methods...
3.
Takahashi N, Gruber C, Yang J, Liu X, Braff D, Yashaswini C, et al.
Proc Natl Acad Sci U S A
. 2017 Aug;
114(34):9164-9169.
PMID: 28794281
Downstream metabolic events can contribute to the lethality of drugs or agents that interact with a primary cellular target. In bacteria, the production of reactive oxygen species (ROS) has been...
4.
Aquino P, Honda B, Jaini S, Lyubetskaya A, Hosur K, Chiu J, et al.
BMC Syst Biol
. 2017 Jan;
11(1):1.
PMID: 28061857
Background: Enteric Escherichia coli survives the highly acidic environment of the stomach through multiple acid resistance (AR) mechanisms. The most effective system, AR2, decarboxylates externally-derived glutamate to remove cytoplasmic protons...
5.
Pardee K, Green A, Takahashi M, Braff D, Lambert G, Lee J, et al.
Cell
. 2016 May;
165(5):1255-1266.
PMID: 27160350
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. Here, we report a pipeline for the...
6.
Braff D, Shis D, Collins J
Adv Drug Deliv Rev
. 2016 Apr;
105(Pt A):35-43.
PMID: 27089812
The growing prevalence of antibiotic resistance calls for new approaches in the development of antimicrobial therapeutics. Likewise, improved diagnostic measures are essential in guiding the application of targeted therapies and...
7.
Dwyer D, Belenky P, Yang J, MacDonald I, Martell J, Takahashi N, et al.
Proc Natl Acad Sci U S A
. 2014 May;
111(20):E2100-9.
PMID: 24803433
Deeper understanding of antibiotic-induced physiological responses is critical to identifying means for enhancing our current antibiotic arsenal. Bactericidal antibiotics with diverse targets have been hypothesized to kill bacteria, in part...