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Dan D Hershko

Explore the profile of Dan D Hershko including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 733
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Recent Articles
1.
Sakran N, Kopelman D, Dar R, Abaya N, Mokary S, Handler C, et al.
Isr Med Assoc J . 2018 Oct; 20(10):627-631. PMID: 30324780
Background: Recent studies have suggested that urgent cholecystectomy is the preferred treatment for acute cholecystitis. However, initial conservative treatment followed by delayed elective surgery is still common practice in many...
2.
Shapira M, Kakiashvili E, Rosenberg T, Hershko D
Breast Cancer Res . 2018 Jul; 20(1):68. PMID: 29986739
After the publication of this work [1], an error was noticed in Fig. 2b, Fig. 3a and Fig. 5b. The Skp1 loading control was accidentally duplicated. We apologize for this...
3.
Hershko D
Future Oncol . 2010 Dec; 6(12):1837-47. PMID: 21142858
The prognosis and clinical management of patients with cancer is commonly determined by traditional clinical and pathological factors. Nevertheless, patients may present with significantly different clinical outcomes despite similar clinicopathological...
4.
Bar-On O, Shapira M, Skorecki K, Hershko A, Hershko D
Cell Cycle . 2010 May; 9(10):1986-9. PMID: 20473026
We have recently shown that Skp2 levels are high in undifferentiated human embryonic stem cells, but decline rapidly following induction of differentiation, thereby leading to accumulation of p27. Changes in...
5.
Nagler R, Ben-Izhak O, Ostrovsky D, Golz A, Hershko D
Cancer Invest . 2009 Mar; 27(5):512-20. PMID: 19296297
Cks1 is an essential factor in facilitating Skp2-dependent degradation of p27, but its role in salivary malignancies is unknown. Expression of cyclin-dependent kinase subunit 1 (Cks1) was examined in 64...
6.
Davidovich S, Ben-Izhak O, Shapira M, Futerman B, Hershko D
Breast Cancer Res . 2008 Jul; 10(4):R63. PMID: 18644126
Introduction: Preoperative chemotherapy is often used in patients with locally advanced breast cancer. However, commonly used clinical and pathological parameters are poor predictors of response to this type of therapy....
7.
Hershko D
Cancer . 2008 Feb; 112(7):1415-24. PMID: 18260093
The expression of Skp2, the ubiquitin ligase subunit that targets p27(Kip1) for degradation, is commonly overexpressed in human cancers. p27(Kip1) is a negative regulator of the cell cycle that plays...
8.
Duek S, Issa N, Hershko D, Krausz M
Dis Colon Rectum . 2008 Feb; 51(4):379-84. PMID: 18236108
Purpose: The use of transanal endoscopic microsurgery for local excision of rectal cancer has recently gained wide acceptance as a valid and safe alternative for the surgical treatment of T1...
9.
Bar-On O, Shapira M, Hershko D
Anticancer Drugs . 2007 Sep; 18(10):1113-21. PMID: 17893511
Overexpression of Skp2, the ubiquitin ligase subunit that targets p27 for degradation, is often observed in cancers, and is associated with aggressive tumor proliferation and poor prognosis. As there is...
10.
Hershko D, Awad N, Fischer D, Mahajna A, Guralnik L, Israelit S, et al.
Dis Colon Rectum . 2007 Jun; 50(8):1223-9. PMID: 17566826
Purpose: Focused helical CT using rectal contrast material only has emerged recently as an accurate diagnostic tool for the evaluation of suspected acute appendicitis. This study was designed to prospectively...