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Damian Oscar Muzzio

Explore the profile of Damian Oscar Muzzio including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 70
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Recent Articles
1.
Krupa P, Wein H, Zemmrich L, Zygmunt M, Muzzio D
Front Immunol . 2024 Sep; 15:1452879. PMID: 39328416
A well-balanced maternal immune system is crucial to maintain fetal tolerance in case of infections during pregnancy. Immune adaptations include an increased secretion of soluble mediators to protect the semi-allogeneic...
2.
Einenkel R, Ehrhardt J, Zygmunt M, Muzzio D
Front Immunol . 2024 Aug; 15:1447190. PMID: 39176096
, involved in carcinogenesis of colon carcinomas, has been described as part of the commensal flora of the female upper reproductive tract. Although its contribution to destructive inflammatory processes is...
3.
Einenkel R, Ehrhardt J, Zygmunt M, Muzzio D
Reprod Biol Endocrinol . 2022 Jul; 20(1):109. PMID: 35906658
Early pregnancy is marked by placentation and embryogenesis, which take place under physiological low oxygen concentrations. This oxygen condition is crucial for many aspects of placentation, trophoblast function, vascularization and...
4.
Heusler M, Einenkel R, Ehrhardt J, Muzzio D, Zygmunt M
Front Immunol . 2021 Sep; 12:698045. PMID: 34531854
Pregnancy success depends greatly on a balanced immune homeostasis. The detection of bacterial components in the upper reproductive tract in non-pregnant and pregnant women raised questions on its possible beneficial...
5.
Valeff N, Juriol L, Quadrana F, Muzzio D, Zygmunt M, Quiroga M, et al.
Front Immunol . 2020 Apr; 11:446. PMID: 32292403
Interleukin-33 (IL-33) is a mucosal alarmin belonging to the IL-1 cytokine family and is now recognized to have a key role in innate and adaptive immunity, contributing to tissue homeostasis...
6.
Einenkel R, Ehrhardt J, Hartmann K, Kruger D, Muzzio D, Zygmunt M
Reproduction . 2020 Mar; 160(1):155-169. PMID: 32130203
Strategically located in mucosal barriers, innate lymphoid cells (ILCs) are relevant in local containment and tolerance of commensal microflora. ILCs have been recently described at the fetomaternal interface, where the...
7.
Frohlich C, Ehrhardt J, Kruger D, Trojnarska D, Zygmunt M, Muzzio D
Reproduction . 2020 Jan; 159(3):351-359. PMID: 31940277
A favorable outcome of pregnancy depends greatly on an adequate balance of immune protection and fetal tolerance at the fetomaternal interface. IL-21 is a pro-inflammatory cytokine associated with altering immune...
8.
Einenkel R, Packhauser K, Ehrhardt J, Tungler A, Zygmunt M, Muzzio D
Reproduction . 2019 Aug; 158(4):323-333. PMID: 31426030
Alterations in the immunologic balance during pregnancy have been associated with poor pregnancy outcomes. The underlying mechanisms are complex and mouse models delivered valuable information on inflammatory imbalance in disturbed...
9.
Einenkel R, Zygmunt M, Muzzio D
Reprod Biol . 2019 Apr; 19(2):113-118. PMID: 31023521
Contrary to the traditional assumption of a sterile uterus, the number of studies characterizing microbial entities in the healthy upper reproductive tract (endometrial cavity, including follicular fluid and placenta) have...
10.
Packhauser K, Roman-Sosa G, Ehrhardt J, Kruger D, Zygmunt M, Muzzio D
Front Immunol . 2017 May; 8:486. PMID: 28491062
For the normal development of pregnancy, a balance between immune tolerance and defense is crucial. However, the mechanisms mediating such a balance are not fully understood. CD83 is a transmembrane...