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Damian J Mole

Explore the profile of Damian J Mole including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 810
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Recent Articles
1.
Soltanzadeh-Naderi Y, Reintam Blaser A, Bjorck M, Nuzzo A, Starkopf J, Forbes A, et al.
Diagnostics (Basel) . 2024 Dec; 14(23). PMID: 39682613
Background: There are no clinical or laboratory markers that can diagnose acute mesenteric ischemia (AMI) accurately. This study aimed to find differences in clinical and laboratory markers between arterial occlusive...
2.
Reintam Blaser A, Mandul M, Bjorck M, Acosta S, Bala M, Bodnar Z, et al.
Crit Care . 2024 Jan; 28(1):32. PMID: 38263058
Background: The aim of this multicentre prospective observational study was to identify the incidence, patient characteristics, diagnostic pathway, management and outcome of acute mesenteric ischaemia (AMI). Methods: All adult patients...
3.
Hayes A, Zheng X, OKelly J, Neyton L, Bochkina N, Uings I, et al.
Cell Rep . 2023 Jul; 42(8):112763. PMID: 37478012
Kynurenine monooxygenase (KMO) blockade protects against multiple organ failure caused by acute pancreatitis (AP), but the link between KMO and systemic inflammation has eluded discovery until now. Here, we show...
4.
Waddell H, Stevenson T, Mole D
Heliyon . 2023 Apr; 9(4):e15335. PMID: 37089281
Circadian rhythms are responsible for governing various physiological processes, including hormone secretion, immune responses, metabolism, and the sleep/wake cycle. In critical illnesses such as acute pancreatitis (AP), circadian rhythms can...
5.
Walker A, OKelly J, Graham C, Nowell S, Kidd D, Mole D
BJS Open . 2022 Dec; 6(6). PMID: 36515672
Background: Acute pancreatitis (AP) is a frequent cause of hospitalization with long-term health consequences, including type 3c diabetes mellitus (DM). The incidence and risk factors for new-onset morbidities after AP...
6.
Puigoriol-Illamola D, Companys-Alemany J, McGuire K, Homer N, Leiva R, Vazquez S, et al.
Pharmaceuticals (Basel) . 2021 Oct; 14(10). PMID: 34681264
Impaired glucocorticoid (GC) signaling is a significant factor in aging, stress, and neurodegenerative diseases such as Alzheimer's disease. Therefore, the study of GC-mediated stress responses to chronic moderately stressful situations,...
7.
Sethi P, Thavanesan N, Welsh F, Connell J, Pickles E, Kelly M, et al.
BJR Case Rep . 2021 Jun; 7(3):20200172. PMID: 34131498
It is not uncommon for clinicians to encounter varying degrees of hepatic steatosis in patients undergoing resection for colorectal liver metastases (CRLM). Magnetic resonance imaging is currently the preferred investigation...
8.
Crittenden S, Goepp M, Pollock J, Robb C, Smyth D, Zhou Y, et al.
Sci Adv . 2021 Feb; 7(7). PMID: 33579710
The gut microbiota fundamentally regulates intestinal homeostasis and disease partially through mechanisms that involve modulation of regulatory T cells (T), yet how the microbiota-T cross-talk is physiologically controlled is incompletely...
9.
Sherif A, McFadyen R, Boyd J, Ventre C, Glenwright M, Walker K, et al.
BMJ Open . 2020 Dec; 10(12):e040200. PMID: 33293311
Introduction: Survivors of acute pancreatitis (AP) have shorter overall survival and increased incidence of new-onset cardiovascular, respiratory, liver and renal disease, diabetes mellitus and cancer compared with the general population,...
10.
Mole D, Fallowfield J, Sherif A, Kendall T, Semple S, Kelly M, et al.
PLoS One . 2020 Dec; 15(12):e0238568. PMID: 33264327
The risk of poor post-operative outcome and the benefits of surgical resection as a curative therapy require careful assessment by the clinical care team for patients with primary and secondary...