Dajia Liu
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Explore the profile of Dajia Liu including associated specialties, affiliations and a list of published articles.
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5
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19
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Recent Articles
1.
Liu D, Guo L, Waasdorp C, Meijer S, Bootsma S, Oyarce C, et al.
Biomed Pharmacother
. 2024 Aug;
178:117261.
PMID: 39106708
Background: Long-term anti-angiogenesis leads to pruned vasculature, densely deposited extracellular matrix (ECM), and consequently reduced chemotherapy delivery in esophagogastric cancer (EGC). To address this issue, we evaluated the efficacy of...
2.
Liu D, van der Zalm A, Koster J, Bootsma S, Oyarce C, van Laarhoven H, et al.
Pharmacol Res
. 2024 Jul;
207:107315.
PMID: 39059615
Epithelial-mesenchymal transition (EMT) has been identified as a driver of therapy resistance, particularly in esophageal adenocarcinoma (EAC), where transforming growth factor beta (TGF-β) can induce this process. Inhibitors of TGF-β...
3.
Henckens S, Liu D, Gisbertz S, Kalff M, Anderegg M, Crull D, et al.
Br J Surg
. 2024 Feb;
111(2).
PMID: 38387083
Background: This study evaluated the association of pathological tumour response (tumour regression grade, TRG) and a novel scoring system, combining both TRG and nodal status (TRG-ypN score; TRG1-ypN0, TRG>1-ypN0, TRG1-ypN+...
4.
Dings M, van der Zalm A, Bootsma S, van Maanen T, Waasdorp C, Ende T, et al.
Cell Rep Med
. 2022 Nov;
3(11):100802.
PMID: 36334593
Neoadjuvant chemoradiotherapy (nCRT) improves outcomes in resectable esophageal adenocarcinoma (EAC), but acquired resistance precludes long-term efficacy. Here, we delineate these resistance mechanisms. RNA sequencing on matched patient samples obtained pre-and...
5.
Liu D, Steins A, Klaassen R, van der Zalm A, Bennink R, van Tienhoven G, et al.
Biomedicines
. 2020 Oct;
8(11).
PMID: 33105540
Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma and a hypoxic microenvironment. Pancreatic stellate cells (PSC) are activated by hypoxia and promote excessive desmoplasia, further contributing to the development...