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Dahlene N Fusco

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Articles 38
Citations 665
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Recent Articles
1.
Zhang B, Fong Y, Dang L, Fintzi J, Chen S, Wang J, et al.
Nat Commun . 2025 Jan; 16(1):759. PMID: 39824819
Neutralizing antibody titer has been a surrogate endpoint for guiding COVID-19 vaccine approval and use, although the pandemic's evolution and the introduction of variant-adapted vaccine boosters raise questions as to...
2.
Fong Y, Dang L, Zhang B, Fintzi J, Chen S, Wang J, et al.
Clin Infect Dis . 2024 Sep; 80(1):223-227. PMID: 39325506
For COVAIL recipients of a coronavirus disease 2019 (COVID-19) Sanofi booster vaccine, neutralizing antibody titers were assessed as a correlate of risk (CoR) of COVID-19. Peak and exposure-proximal titers were...
3.
Sise M, Santos J, Goldman J, Tuttle K, Teixeira J, Seibert A, et al.
Clin Infect Dis . 2024 Jun; 79(5):1172-1181. PMID: 38913574
Background: Few antiviral therapies have been studied in patients with coronavirus disease 2019 (COVID-19) and kidney impairment. Herein, the efficacy, safety, and pharmacokinetics of remdesivir, its metabolites, and sulfobutylether-β-cyclodextrin excipient...
4.
Salvadori N, Fridman M, Chiang M, Chen L, Wang C, Lee E, et al.
Front Med (Lausanne) . 2024 May; 11:1390164. PMID: 38818394
Background: The direct acting antiviral remdesivir (RDV) has shown promising results in randomized clinical trials. This study is a unique report of real clinical practice RDV administration for COVID-19 from...
5.
Branche A, Rouphael N, Diemert D, Falsey A, Losada C, Baden L, et al.
Nat Med . 2023 Aug; 29(9):2334-2346. PMID: 37640860
Vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized clinical trial with sequentially enrolled stages at...
6.
Rouphael N, Branche A, Diemert D, Falsey A, Losada C, Baden L, et al.
J Infect Dis . 2023 Aug; 228(12):1662-1666. PMID: 37561027
We compared the serologic responses of 1 dose versus 2 doses of a variant vaccine (Moderna mRNA-1273 Beta/Omicron BA.1 bivalent vaccine) in adults. A 2-dose boosting regimen with a variant...
7.
Rouphael N, Branche A, Diemert D, Falsey A, Losada C, Baden L, et al.
medRxiv . 2023 Jun; PMID: 37333252
In this brief report, we compare the magnitude and durability of the serologic response of one versus two doses (separated by 56 days) of a variant vaccine (Moderna mRNA-1273 Beta/Omicron...
8.
Branche A, Rouphael N, Losada C, Baden L, Anderson E, Luetkemeyer A, et al.
Clin Infect Dis . 2023 Apr; 77(4):560-564. PMID: 37036397
In a randomized clinical trial, we compare early neutralizing antibody responses after boosting with bivalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA (mRNA) vaccines based on either BA.1...
9.
Branche A, Rouphael N, Losada C, Baden L, Anderson E, Luetkemeyer A, et al.
medRxiv . 2023 Apr; PMID: 37034641
In a randomized clinical trial, we compare early neutralizing antibody responses after boosting with bivalent SARS-CoV-2 mRNA vaccines based on either BA.1 or BA.4/BA.5 Omicron spike protein combined with wildtype...
10.
Branche A, Rouphael N, Diemert D, Falsey A, Losada C, Baden L, et al.
medRxiv . 2022 Jul; PMID: 35898343
Background: Protection from SARS-CoV-2 vaccines wanes over time and is compounded by emerging variants including Omicron subvariants. This study evaluated safety and immunogenicity of SARS-CoV-2 variant vaccines. Methods: This phase...