Dagmar Scheel-Toellner
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Explore the profile of Dagmar Scheel-Toellner including associated specialties, affiliations and a list of published articles.
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37
Citations
938
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Recent Articles
1.
Bell R, Brendel M, Konnaris M, Xiang J, Otero M, Fontana M, et al.
Nat Commun
. 2024 Aug;
15(1):7503.
PMID: 39209814
Rheumatoid arthritis (RA) is a complex immune-mediated inflammatory disorder in which patients suffer from inflammatory-erosive arthritis. Recent advances on histopathology heterogeneity of RA synovial tissue revealed three distinct phenotypes based...
2.
Sahlstrom P, Joshua V, Valkovskaia V, Biese C, Stalesen R, Israelsson L, et al.
J Biol Chem
. 2023 Oct;
299(11):105320.
PMID: 37802315
Autoantibodies to malondialdehyde (MDA) proteins constitute a subset of anti-modified protein autoantibodies in rheumatoid arthritis (RA), which is distinct from citrulline reactivity. Serum anti-MDA IgG levels are commonly elevated in...
3.
Vidal-Pedrola G, Naamane N, Cameron J, Pratt A, Mellor A, Isaacs J, et al.
Immunology
. 2022 Oct;
168(4):640-653.
PMID: 36281956
Age-associated B cells (ABCs) are an immune cell subset linked to autoimmunity, infection and ageing, and whose pathophysiological importance was recently highlighted using single cell synovial tissue profiling. To elucidate...
4.
Patel A, Liu Y, Davies S, Brown R, Kelly D, Scheel-Toellner D, et al.
Front Immunol
. 2021 Oct;
12:729143.
PMID: 34630404
B lymphocytes are multitasking cells that direct the immune response by producing pro- or anti-inflammatory cytokines, by presenting processed antigen for T cell activation and co-stimulation, and by turning into...
5.
Schiffer L, Bossey A, Kempegowda P, Taylor A, Akerman I, Scheel-Toellner D, et al.
Eur J Endocrinol
. 2021 Jan;
184(3):353-363.
PMID: 33444228
Objective: Androgens are important modulators of immune cell function. The local generation of active androgens from circulating precursors is an important mediator of androgen action in peripheral target cells or...
6.
Carr H, Turner J, Major T, Scheel-Toellner D, Filer A
Front Med (Lausanne)
. 2020 Feb;
7:21.
PMID: 32083090
Transcriptomic technologies are constantly changing and improving, resulting in an ever increasing understanding of gene expression in health and disease. These technologies have been used to investigate the pathological changes...
7.
Zhao Y, Uduman M, Siu J, Tull T, Sanderson J, Wu Y, et al.
Nat Commun
. 2018 Sep;
9(1):3857.
PMID: 30242242
Human memory B cells and marginal zone (MZ) B cells share common features such as the expression of CD27 and somatic mutations in their IGHV and BCL6 genes, but the...
8.
Amara K, Clay E, Yeo L, Ramskold D, Spengler J, Sippl N, et al.
Data Brief
. 2017 Jul;
13:356-370.
PMID: 28664171
This manuscript is a companion paper to Amara et al. [1]. Data shown here include detailed clinical characteristics from anonymized patients, the Ig subclass data generated from B cells sorted...
9.
Gronwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engstrom M, et al.
J Autoimmun
. 2017 Jun;
84:29-45.
PMID: 28647488
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated...
10.
Amara K, Clay E, Yeo L, Ramskold D, Spengler J, Sippl N, et al.
J Autoimmun
. 2017 Mar;
81:34-43.
PMID: 28343748
The clinical efficacy of B cell targeting therapies highlights the pathogenic potential of B cells in inflammatory diseases. Expression of Fc Receptor like 4 (FcRL4) identifies a memory B cell...