Dagmar K Willkomm
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Explore the profile of Dagmar K Willkomm including associated specialties, affiliations and a list of published articles.
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17
Citations
182
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Recent Articles
1.
Walczyk D, Willkomm D, Hartmann R
RNA
. 2016 Sep;
22(11):1699-1709.
PMID: 27604960
Ribonuclease P is the ubiquitous endonuclease that generates the mature 5'-ends of precursor tRNAs. In bacteria, the enzyme is composed of a catalytic RNA (∼400 nucleotides) and a small essential...
2.
Kondo J, Dock-Bregeon A, Willkomm D, Hartmann R, Westhof E
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2013 Jun;
69(Pt 6):634-9.
PMID: 23722840
In the course of a crystallographic study of a 132 nt variant of Aquifex aeolicus 6S RNA, a crystal structure of an A-form RNA duplex containing 12 base pairs was...
3.
Beckmann B, Hoch P, Marz M, Willkomm D, Salas M, Hartmann R
EMBO J
. 2012 Feb;
31(7):1727-38.
PMID: 22333917
Bacillus subtilis 6S-1 RNA binds to the housekeeping RNA polymerase (σ(A)-RNAP) and directs transcription of short 'product' RNAs (pRNAs). Here, we demonstrate that once newly synthesized pRNAs form a sufficiently...
4.
Li D, Meyer M, Willkomm D, Keusgen M, Hartmann R
Biochimie
. 2010 Mar;
92(7):772-8.
PMID: 20211679
A magnetic sensor technique was applied to analyze the interaction of immobilized bacterial RNase P protein and 3'-biotinylated RNase P RNA bound to streptavidin-coated magnetic beads. Our measurements with three...
5.
Li D, Willkomm D, Hartmann R
Nucleic Acids Res
. 2008 Nov;
37(1):231-42.
PMID: 19036794
The increased protein proportion of archaeal and eukaryal ribonuclease (RNase) P holoenzymes parallels a vast decrease in the catalytic activity of their RNA subunits (P RNAs) alone. We show that...
6.
Marszalkowski M, Willkomm D, Hartmann R
Biol Chem
. 2008 Jan;
389(4):395-403.
PMID: 18208351
5'-End maturation of tRNA primary transcripts is thought to be ubiquitously catalyzed by ribonuclease P (RNase P), a ribonucleoprotein enzyme in the vast majority of organisms and organelles. In the...
7.
Marszalkowski M, Willkomm D, Hartmann R
RNA
. 2007 Nov;
14(1):127-33.
PMID: 17998289
For stability, many catalytic RNAs rely on long-range tertiary interactions, the precise role of each often being unclear. Here we demonstrate that one of the three interdomain architectural struts of...
8.
Li D, Willkomm D, Schon A, Hartmann R
Biochimie
. 2007 Sep;
89(12):1528-38.
PMID: 17881113
Ribonuclease P (RNase P) is a ribonucleoprotein enzyme that generates the mature 5' ends of tRNAs. Ubiquitous across all three kingdoms of life, the composition and functional contributions of the...
9.
Willkomm D, Hartmann R
Trends Biochem Sci
. 2007 May;
32(6):247-50.
PMID: 17485211
RNase P is the ribonucleoprotein enzyme that generates the mature 5' ends of tRNAs throughout all three kingdoms of life. Long known to function as a ribozyme in bacteria and...
10.
Marszalkowski M, Teune J, Steger G, Hartmann R, Willkomm D
RNA
. 2006 Sep;
12(11):1915-21.
PMID: 17005927
The RNase P RNA (rnpB) and protein (rnpA) genes were identified in the two Aquificales Sulfurihydrogenibium azorense and Persephonella marina. In contrast, neither of the two genes has been found...