» Authors » Dafne Franz Demane

Dafne Franz Demane

Explore the profile of Dafne Franz Demane including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 4
Citations 220
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Yofe I, Landsberger T, Yalin A, Solomon I, Costoya C, Demane D, et al.
Nat Cancer . 2022 Nov; 3(11):1404. PMID: 36376510
No abstract available.
2.
Yofe I, Landsberger T, Yalin A, Solomon I, Costoya C, Demane D, et al.
Nat Cancer . 2022 Oct; 3(11):1336-1350. PMID: 36302895
Despite the clinical success of checkpoint inhibitors, a substantial gap still exists in our understanding of their mechanism of action. While antibodies to cytotoxic T lymphocyte-associated protein-4 (CTLA-4) were developed...
3.
Solomon I, Amann M, Goubier A, Vargas F, Zervas D, Qing C, et al.
Nat Cancer . 2021 Mar; 1(12):1153-1166. PMID: 33644766
Intratumoral regulatory T cell (Treg) abundance associates with diminished anti-tumor immunity and poor prognosis in human cancers. Recent work demonstrates that CD25, the high affinity receptor subunit for IL-2, is...
4.
Sledzinska A, Vila de Mucha M, Bergerhoff K, Hotblack A, Demane D, Ghorani E, et al.
Immunity . 2020 Jan; 52(1):151-166.e6. PMID: 31924474
In addition to helper and regulatory potential, CD4 T cells also acquire cytotoxic activity marked by granzyme B (GzmB) expression and the ability to promote rejection of established tumors. Here,...