Dachang Bai
Overview
Explore the profile of Dachang Bai including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
68
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yin T, Sui S, Li S, Chang J, Bai D
Chem Commun (Camb)
. 2024 Nov;
60(96):14204-14207.
PMID: 39530918
Enantioenriched organosilanes are important chiral molecules in materials science and organic synthesis. The synthesis of axially chiral organosilanes is particularly significant in terms of applications. Herein, we report a Ni-catalyzed...
2.
Yin T, Jin M, Zhao T, Chang J, Bai D
Org Lett
. 2024 Sep;
26(38):8194-8199.
PMID: 39270207
Enantioenriched monofluoroalkenes are important structural motifs in life science and functional materials. To date, only limited strategies were reported for the synthesis of monofluoroalkenes with stereogenic carbon centers; the axially...
3.
Bai D, Zhong K, Chang L, Qiao Y, Wu F, Xu G, et al.
Nat Commun
. 2024 Jul;
15(1):6360.
PMID: 39069515
The fluoroalkyl-containing organic molecules are widely used in drug discovery and material science. Herein, we report ligand regulated nickel(0)-catalyzed regiodivergent hydrosilylation of α-(fluoroalkyl)styrenes without defluorination, providing an atom- and step-economical...
4.
Wu F, Chang J, Bai D
Org Lett
. 2024 May;
26(23):4953-4957.
PMID: 38815137
Organofluorine compounds are of high value in medicinal and agricultural chemistry. Herein, we report a palladium-catalyzed fluoro-alkoxylation of -difluoroalkenes for the synthesis of much more challenging sterically hindered ethers. This...
5.
Bai D, Guo X, Wang X, Xu W, Cheng R, Wei D, et al.
Nat Commun
. 2024 Apr;
15(1):2833.
PMID: 38565533
Umpolung is an old and important concept in organic chemistry, which significantly expands the chemical space and provides unique structures. While, previous research focused on carbonyls or imine derivatives, the...
6.
Guo Y, Tian Z, Ma C, Han Y, Bai D, Jiang Z
Chem Sci
. 2023 Nov;
14(42):11907-11913.
PMID: 37920353
Benzene ring contractions are useful yet rare reactions that offer a convenient synthetic route to various valuable chemicals. However, the traditional methods of benzene contraction rely on noble-metal catalysts under...
7.
Bai D, Guo Y, Ma D, Guo X, Wu H
Org Lett
. 2023 Jan;
25(3):533-537.
PMID: 36637250
The difluoromethyl group (CFH) is of great importance in medicinal chemistry. We report herein an efficient method for the synthesis of diversified α-difluoromethyl amines through copper-catalyzed hydroamination of -difluoroalkenes, where...
8.
Bai D, Wu F, Chang L, Wang M, Wu H, Chang J
Angew Chem Int Ed Engl
. 2021 Dec;
61(10):e202114918.
PMID: 34957676
The synthesis of small organic molecules with a difluoromethylated stereocenter is particularly attractive in drug discovery. Herein, we have developed an efficient method for the direct generation of difluoromethylated stereocenters...
9.
Xu G, Chen Q, Wu F, Bai D, Chang J, Li X
Org Lett
. 2021 Mar;
23(8):2927-2932.
PMID: 33787271
Rh(III)-catalyzed C-H activation of -phenoxyacetamides and chemodivergent coupling to alkylidenecyclopropanes (ACPs) have been accomplished. With the assistance of the ring strain of ACPs, the coupling can be transannulative or nonannulative,...
10.
Cui Y, Bai D, Liu B, Chang J, Li X
Chem Commun (Camb)
. 2020 Dec;
56(100):15631-15634.
PMID: 33283807
Rhodium(iii)-catalyzed C-H acylation of heteroarenes has been realized using cyclobutenones as an acylating reagent. This coupling proceeded via integration of C-H activation of heteroarenes and C-C cleavage of cyclobutenones. The...