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D Zochowska

Explore the profile of D Zochowska including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 29
Followers 0
Related Specialty
General Surgery
Top 10 Co-Authors
L Paczek
E Samborowska
E Hryniewiecka
R Jazwiec
J Zegarska
M Dadlez
W Tszyrsznic
S Nazarewski
A Borowiec
I Bartlomiejczyk
Published In
Transplant Proc
Affiliations
Soon will be listed here.
Recent Articles
1.
Evaluation of the Relationship Between Concentrations of Tacrolimus Metabolites, 13-O-Demethyl Tacrolimus and 15-O-Demethyl Tacrolimus, and Clinical and Biochemical Parameters in Kidney Transplant Recipients
Zegarska J, Hryniewiecka E, Zochowska D, Samborowska E, Jazwiec R, Maciej K, et al.
Transplant Proc . 2018 Sep; 50(7):2235-2239. PMID: 30177142
Background: Tacrolimus (Tac), an essential component of immunosuppressive therapy after solid-organ transplantation, has a narrow therapeutic index and requires therapeutic drug monitoring. Monitoring of Tac predose blood concentrations seems to...
2.
Cardiovascular Disease in Kidney Transplantation and Its Association With Blood Concentrations of Cyclosporine and Cyclosporine Metabolites
Hryniewiecka E, Zegarska J, Zochowska D, Samborowska E, Jazwiec R, Kosieradzki M, et al.
Transplant Proc . 2018 Jul; 50(6):1850-1854. PMID: 30056914
Cyclosporine A (CsA) is the first calcineurin inhibitor used as immunosuppressive agent. Its administration is associated with multiple adverse effects including cardiovascular diseases (CVDs), but their mechanisms have not been...
3.
Determination of Concentrations of Azathioprine Metabolites 6-Thioguanine and 6-Methylmercaptopurine in Whole Blood With the Use of Liquid Chromatography Combined With Mass Spectrometry
Zochowska D, Zegarska J, Hryniewiecka E, Samborowska E, Jazwiec R, Tszyrsznic W, et al.
Transplant Proc . 2016 Aug; 48(5):1836-9. PMID: 27496503
Background: 6-Mercaptopurine (6-MP) and its prodrug azathioprine (AZA) are used in many autoimmune diseases and after solid-organ transplantation. Their properties are mediated by active metabolites, 6-thioguanine nucleotides (6-TGN), and 6-methylmercaptopurine...
4.
Hydroxylated, Hydroxymethylated, Dihydroxylated, and Trihydroxylated Cyclosporine Metabolites Can Be Nephrotoxic in Kidney Transplant Recipients
Hryniewiecka E, Zegarska J, Zochowska D, Jazwiec R, Borowiec A, Samborowska E, et al.
Transplant Proc . 2016 Aug; 48(5):1551-5. PMID: 27496445
Background: Cyclosporine (CsA) is an immunosuppressive agent whose use is associated with adverse effects, including nephrotoxicity. There are reports indicating that some CsA metabolites may contribute to these effects. This...
5.
Tacrolimus Metabolite M-III May Have Nephrotoxic and Myelotoxic Effects and Increase the Incidence of Infections in Kidney Transplant Recipients
Zegarska J, Hryniewiecka E, Zochowska D, Samborowska E, Jazwiec R, Borowiec A, et al.
Transplant Proc . 2016 Aug; 48(5):1539-42. PMID: 27496443
Background: Tacrolimus (Tac) is one of the most commonly used immunosuppressive drugs after solid organ transplantation. Eight Tac metabolites have been described, but their clinical importance remains unclear. The aim...
6.
Therapeutic monitoring of tacrolimus concentrations in blood of renal and liver transplant recipients: comparison of microparticle enzyme immunoassay and enzyme multiplied immunoassay methods
Bartlomiejczyk I, Zochowska D, Sanko-Resmer J, Matuszewicz D, Paczek L
Transplant Proc . 2006 Mar; 38(1):94-6. PMID: 16504673
Monitoring of tacrolimus blood concentrations is of utmost importance in the management of organ transplant recipients due to narrow therapeutic index of the drug and its considerable interpatient variability in...
7.
High-performance liquid chromatography versus immunoassay for the measurement of sirolimus: comparison of two methods
Zochowska D, Bartlomiejczyk I, Kaminska A, Senatorski G, Paczek L
Transplant Proc . 2006 Mar; 38(1):78-80. PMID: 16504669
Sirolimus is an immunosuppressive agent administered as prophylaxis of acute rejection to patients after kidney transplantation. Therapeutic drug monitoring (TDM) of whole blood is an important part of immunosuppressive therapy....