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D W Busija

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Articles 149
Citations 956
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Recent Articles
1.
Kis B, Snipes J, Gaspar T, Lenzser G, Tulbert C, Busija D
Inflamm Res . 2006 Sep; 55(7):274-8. PMID: 16955389
Objectives: To clone and sequence cyclooxygenase-1b (COX-1b, also known as COX-3) mRNA and to generate an antibody against the mouse COX-1b protein and to demonstrate its existence in vivo in...
2.
Horiguchi T, Snipes J, Kis B, Shimizu K, Busija D
Neuroscience . 2006 Mar; 140(2):723-30. PMID: 16567054
We examined the role of cyclooxygenase-2 in the development of ischemic tolerance induced by cortical spreading depression against transient, focal brain ischemia. Cortical spreading depression was continuously induced for 2...
3.
Busija D, Miller A, Katakam P, Erdos B
Minerva Med . 2005 Sep; 96(4):223-32. PMID: 16179890
Insulin resistance (IR) has profound, negative effects on the function of arteries and arterioles throughout the body and leads to arterial hypertension and vascular occlusive diseases such as heart attacks...
4.
Kis B, Snipes J, Deli M, Abraham C, Yamashita H, Ueta Y, et al.
Acta Neurochir Suppl . 2004 Feb; 86:565-8. PMID: 14753507
We previously found that the production of adrenomedullin (AM) is one magnitude higher in cerebral endothelial cells (CECs) than in the peripheral endothelium and the AM concentration in the cerebral...
5.
Lacza Z, Puskar M, Figueroa J, Zhang J, Rajapakse N, Busija D
Free Radic Biol Med . 2001 Dec; 31(12):1609-15. PMID: 11744335
Nitric oxide is a potent modulator of mitochondrial respiration, ATP synthesis, and K(ATP) channel activity. Recent studies show the presence of a potentionally new isoform of the nitric oxide synthase...
6.
Domoki F, Perciaccante J, Puskar M, Bari F, Busija D
Neuroreport . 2001 Dec; 12(18):4065-8. PMID: 11742239
Anoxic stress attenuates NMDA-induced pial arteriolar dilation via a mechanism involving actions of cyclooxygenase (COX)-derived reactive oxygen species (ROS). We examined whether the selective COX-2 inhibitor NS398 would protect neuronal...
7.
Miller A, Dimitropoulou C, Han G, White R, Busija D, Carrier G
Am J Physiol Heart Circ Physiol . 2001 Sep; 281(4):H1524-31. PMID: 11557540
We assessed the effect of epoxyeicosatrienoic acids (EETs) in intact mesenteric arteries and Ca(2+)-activated K(+) (BK(Ca)) channels of isolated vascular smooth muscle cells from control and insulin-resistant (IR) rats. The...
8.
Degi R, Thore C, Bari F, Thrikawala N, Nogradi A, Robins G, et al.
Graefes Arch Clin Exp Ophthalmol . 2001 Mar; 239(1):59-65. PMID: 11271464
Background: Ischemia increases levels of prostaglandin H synthase-2 (PGHS-2) in neonatal brain and cerebral vasculature, but effects on the developing visual system are unknown. We examined the effects of ischemia...
9.
Domoki F, Thrikawala N, Robins G, Bari F, Busija D
Neuroreport . 2000 Nov; 11(16):3435-8. PMID: 11095494
Ischemia/reperfusion (I/R) results in a robust induction of cyclooxygenase (COX)-2 in the newborn brain via unknown mechanisms, but glutamate release and activation of KA receptors may be involved. We examined...
10.
Shimizu K, Bari F, Busija D
Neuroreport . 2000 Aug; 11(10):2103-6. PMID: 10923652
We investigated the contribution of ATP-sensitive potassium channels (K(ATP)) and calcium-activated potassium channels (Kca2+) to cortical spreading depression (CSD)-associated hyperemia using the rat closed cranial window model. The peak CBF...