D T Yapp
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Explore the profile of D T Yapp including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
30
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Recent Articles
1.
Verreault M, Wehbe M, Strutt D, Masin D, Anantha M, Walker D, et al.
J Control Release
. 2015 Nov;
220(Pt A):348-357.
PMID: 26528901
Our laboratory reported that Irinophore C™ (IrC™; a lipid-based nanoparticulate formulation of irinotecan) is effective against an orthotopic model of glioblastoma (GBM) and that treatment with IrC™ was associated with...
2.
Verreault M, Strutt D, Masin D, Anantha M, Waterhouse D, Yapp D, et al.
J Control Release
. 2011 Oct;
158(1):34-43.
PMID: 22001870
Given compelling evidences supporting the therapeutic potential of irinotecan (IRN) for patients with glioblastoma (GBM), the present study evaluated the activity of Irinophore C™ (IrC™), a lipid-based nanopharmaceutical formulation of...
3.
Yapp D, Lloyd D, Zhu J, Lehnert S
Radiother Oncol
. 2000 Jan;
53(1):77-84.
PMID: 10624857
Background And Purpose: Drug toxicities are often a limiting factor in long term treatment regimes used in conjunction with radiotherapy. If the drug could be localized to the tumor site...
4.
Doiron A, Yapp D, Olivares M, Zhu J, Lehnert S
Cancer Res
. 1999 Aug;
59(15):3677-81.
PMID: 10446981
We have previously reported that the use of the polymer bis(p-carboxyphenoxy)propane-sebacic acid (20:80) for intratumoral delivery of cis-platinum in a mouse tumor model (RIF-1) potentiated the effects of acute and...
5.
Yapp D, Lloyd D, Zhu J, LEHNERT S
Anticancer Drugs
. 1998 Dec;
9(9):791-6.
PMID: 9840725
The use of biodegradable polymer implants to deliver cisplatin was compared with delivery by systemic injection and by osmotic pump. Drug levels in the tumor were found to be higher...
6.
Yapp D, Lloyd D, Zhu J, LEHNERT S
Int J Radiat Oncol Biol Phys
. 1998 Oct;
42(2):413-20.
PMID: 9788424
Purpose: To compare potentiation of the effects of acute or fractionated radiation by cisplatin when the drug was delivered intratumorally by implanted biodegradable polymer, by intraperitoneal injection, or by intraperitoneal...
7.
Yapp D, Lloyd D, Zhu J, LEHNERT S
Int J Radiat Oncol Biol Phys
. 1997 Oct;
39(2):497-504.
PMID: 9308956
Purpose: The effect of intratumoral delivery of cisplatin to a mouse tumor model (RIF-1) by means of a biodegradable polymer implant with and without radiation was studied. Methods And Materials:...