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D Soderlund

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Citations 153
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Recent Articles
1.
Canto P, Munguia P, Soderlund D, Castro J, Mendez J
J Androl . 2008 Aug; 30(1):41-5. PMID: 18723471
Kallmann syndrome (KS) is characterized by the association of hypogonadotropic hypogonadism and anosmia or hyposmia. To date, 4 different genes have been identified as responsible for the presence of KS;...
2.
Canto P, Vilchis F, Soderlund D, Reyes E, Mendez J
Mol Hum Reprod . 2006 Jan; 11(11):833-6. PMID: 16390857
Aetiology of mixed gonadal dysgenesis (MGD) has not been completely elucidated. Molecular analyses have failed to demonstrate the presence of mutations in sex-determining region on Y chromosome (SRY); it has...
3.
Soderlund D, Canto P, Carranza-Lira S, Mendez J
Hum Reprod . 2005 Feb; 20(4):965-9. PMID: 15695318
Background: Etiology and inheritance pattern in polycystic ovary syndrome (PCOS) remain uncertain. Granulosa cells from follicles of women with PCOS have little, if any, aromatase (encoded by the CYP19 gene)...
4.
Soderlund D, Vilchis F, Mendez J
J Endocrinol Invest . 2005 Jan; 27(8):765-9. PMID: 15636431
The KAL1 gene has a closely related nonfunctional pseudogene on the Y chromosome; a high degree of X-Y sequence similarity is observed. Some individuals present a T to C substitution...
5.
Canto P, Soderlund D, Reyes E, Mendez J
J Clin Endocrinol Metab . 2004 Sep; 89(9):4480-3. PMID: 15356051
Mutations of SRY are the cause of complete pure gonadal dysgenesis (PGD) in 10-15% of patients. In the remaining individuals, it has been suggested that mutations in other genes involved...
6.
Olivares A, Soderlund D, Castro-Fernandez C, Zarinan T, Zambrano E, Mendez J, et al.
Endocrine . 2004 May; 23(2-3):189-98. PMID: 15146100
Follicle-stimulating hormone is synthesized and secreted as a mixture of heterogeneous isoforms that differ from each other in carbohydrate structure, biological potency, and plasma half-life. The relative abundance of the...
7.
Soderlund D, Canto P, Mendez J
J Clin Endocrinol Metab . 2002 Jun; 87(6):2589-92. PMID: 12050219
Kallmann's syndrome (KS) is characterized by the association of hypogonadotropic hypogonadism and anosmia or hyposmia. Genetic defects have been observed throughout the KAL1 gene, located on the Xp22.3 region, in...
8.
Zarinan T, Olivares A, Soderlund D, Mendez J, Ulloa-Aguirre A
Hum Reprod . 2001 Jul; 16(8):1611-8. PMID: 11473951
Background: Significant changes in charge isoform distribution of serum FSH occur throughout the human menstrual cycle. In the present study, we analysed the impact of the changing endocrine milieu characteristic...
9.
Soderlund D, Canto P, de la Chesnaye E, Ulloa-Aguirre A, Mendez J
Clin Endocrinol (Oxf) . 2001 Apr; 54(4):493-8. PMID: 11318785
Background And Objective: Mutations in the GnRH receptor (GnRH-R) gene cause hypogonadotrophic hypogonadism. Here, we present the molecular studies of the GnRH-R gene in three families with isolated hypogonadotrophic hypogonadism....
10.
Castro-Fernandez C, Olivares A, Soderlund D, Lopez-Alvarenga J, Zambrano E, Veldhuis J, et al.
J Clin Endocrinol Metab . 2001 Jan; 85(12):4603-10. PMID: 11134115
Hormonal abnormalities of the reproductive axis have been described in obesity. In men, extreme obesity is associated with low serum testosterone (T) and high estrogen [estrone and estradiol (E(2))] levels....