D S Steinbrech
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Explore the profile of D S Steinbrech including associated specialties, affiliations and a list of published articles.
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29
Citations
495
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Recent Articles
11.
Steinbrech D, Mehrara B, Rowe N, Dudziak M, Luchs J, Saadeh P, et al.
Plast Reconstr Surg
. 2000 Jun;
105(6):2028-38.
PMID: 10839400
Poorly healing mandibular fractures and osteotomies can be troublesome complications of craniomaxillofacial trauma and reconstructive surgery. Gene therapy may offer ways of enhancing bone formation by altering the expression of...
12.
Saadeh P, Mehrara B, Steinbrech D, Spector J, GREENWALD J, Chin G, et al.
Endocrinology
. 2000 Jun;
141(6):2075-83.
PMID: 10830293
Normal bone growth and repair is dependent on angiogenesis. Fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and transforming growth factor-beta (TGFbeta) have all been implicated in the related...
13.
Steinbrech D, Mehrara B, Saadeh P, GREENWALD J, Spector J, Gittes G, et al.
Ann Plast Surg
. 2000 May;
44(5):529-34; discussion 534-5.
PMID: 10805305
Vascular disruption secondary to fracture leads to a hypoxic zone of injury where the oxygen tension at the center of the wound is quite low. In this dynamic microenvironment, a...
14.
Spector J, Mehrara B, Luchs J, GREENWALD J, Fagenholz P, Saadeh P, et al.
Ann Plast Surg
. 2000 May;
44(5):522-8.
PMID: 10805304
Gene therapy has moved from the promise of laboratory investigation to the reality of clinical practice in just the last decade. Various methods for delivery of genes to host cells...
15.
GREENWALD J, Mehrara B, Spector J, Chin G, Steinbrech D, Saadeh P, et al.
Plast Reconstr Surg
. 2000 Apr;
105(4):1382-92.
PMID: 10744229
The ability of newborns and immature animals to reossify calvarial defects has been well described. This capacity is generally lost in children greater than 2 years of age and in...
16.
Frenkel S, Saadeh P, Mehrara B, Chin G, Steinbrech D, Brent B, et al.
Plast Reconstr Surg
. 2000 Mar;
105(3):980-90.
PMID: 10724258
Normal and abnormal extracellular matrix turnover is thought to result, in part, from the balance in the expression of metalloproteinases and tissue inhibitors of metalloproteinases (TIMPs). The clinical manifestations of...
17.
Mehrara B, Greenwald J, Chin G, Dudziak M, Sagrioglu J, Steinbrech D, et al.
Plast Reconstr Surg
. 2000 Feb;
104(4):1003-13.
PMID: 10654740
A significant body of literature supports a role for the dura mater underlying cranial sutures in the regulation of sutural fate. These studies have implicated regional differentiation of the dura...
18.
Saadeh P, Mehrara B, Steinbrech D, Dudziak M, GREENWALD J, Luchs J, et al.
Am J Physiol
. 1999 Oct;
277(4):C628-37.
PMID: 10516092
Angiogenesis is essential to both normal and pathological bone physiology. Vascular endothelial growth factor (VEGF) has been implicated in angiogenesis, whereas transforming growth factor-beta1 (TGF-beta1) modulates bone differentiation, matrix formation,...
19.
Mehrara B, Saadeh P, Steinbrech D, Dudziak M, Spector J, GREENWALD J, et al.
J Bone Miner Res
. 1999 Aug;
14(8):1290-301.
PMID: 10457261
Modulation of biological pathways governing osteogenesis may accelerate osseous regeneration and reduce the incidence of complications associated with fracture healing. Transforming growth factor beta1 (TGF-beta1) is a potent growth factor...
20.
Steinbrech D, Mehrara B, Saadeh P, Chin G, Dudziak M, Gerrets R, et al.
Plast Reconstr Surg
. 1999 Aug;
104(3):738-47.
PMID: 10456527
Numerous studies have demonstrated the critical role of angiogenesis for successful osteogenesis during endochondral ossification and fracture repair. Vascular endothelial growth factor (VEGF), a potent endothelial cell-specific cytokine, has been...