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D S Cox

Explore the profile of D S Cox including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 371
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Recent Articles
1.
Tolcher A, Bendell J, Papadopoulos K, Burris 3rd H, Patnaik A, Jones S, et al.
Ann Oncol . 2014 Oct; 26(1):58-64. PMID: 25344362
Background: This phase Ib trial investigated the safety, tolerability, and recommended phase II dose and schedule of the MEK inhibitor trametinib in combination with the mammalian target of rapamycin (mTOR)...
2.
Young G, Boshkov L, Sullivan J, Raffini L, Cox D, Boyle D, et al.
Pediatr Blood Cancer . 2011 Apr; 56(7):1103-9. PMID: 21488155
Background: An increasing number of pediatric patients suffer from thrombotic events necessitating anticoagulation therapy including heparins. Some such patients develop heparin-induced thrombocytopenia (HIT) and thus require alternative anticoagulation. As such,...
3.
Cox D, Scott K, Gao H, Raje S, Eddington N
J Pharm Sci . 2001 Dec; 90(10):1540-52. PMID: 11745712
Previous in vitro studies evaluating the permeability of enaminones suggested that their blood-brain barrier (BBB) transport might be influenced by the presence of an efflux mechanism. Therefore, transport mechanisms responsible...
4.
Cox D, Gao H, Raje S, Scott K, Eddington N
Eur J Pharm Biopharm . 2001 Aug; 52(2):145-50. PMID: 11522479
Zonula occludens toxin (Zot), a protein elaborated from Vibrio cholerae, has been shown to be capable of reversibly opening tight junctions between intestinal cells The objective of this study was...
5.
Cox D, Du J, Scott K, Gao H, Eddington N
J Chromatogr B Biomed Sci Appl . 2001 Jan; 749(2):191-6. PMID: 11145056
Enaminone derivatives of the 4-carbomethoxy-5-methylcyclohexane-1,3-dione series represent a new and potentially active series of compounds for the treatment of Epilepsy. Enaminone esters have been previously evaluated as compounds with potent...
6.
Eddington N, Cox D, Roberts R, Stables J, Powell C, Scott K
Curr Med Chem . 2000 Mar; 7(4):417-36. PMID: 10702617
Enaminones, enamines of ss-dicarbonyl compounds, have been know for many years. In our initial account (Current Med. Chem. 1994, 1, 159-175), we reported on the anticonvulsant activity of a series...
7.
Burstein A, Cox D, Mistry B, Eddington N
Epilepsy Res . 1999 Apr; 34(2-3):129-33. PMID: 10210027
The administration of phenytoin suspension in conjunction with enteral nutrition supplements through nasogastric (NG) feeding tubes to humans has been associated with suboptimal phenytoin absorption, subtherapeutic concentrations, and breakthrough seizures....
8.
Marcus A, Morra M, Rimer B, Stricker M, HEIMENDINGER J, Wolfe P, et al.
Prev Med . 1998 May; 27(2):250-61. PMID: 9579004
Background: In this paper, results are reported from a pilot study designed to test the feasibility of a proactive educational intervention delivered to callers of the Cancer Information Service (CIS)....
9.
Stone A, Marco C, Cruise C, Cox D, Neale J
Int J Behav Med . 1996 Jan; 3(1):1-13. PMID: 16250763
This investigation tested a three-path model of mood as a mediator of the relation between stress and immunity. Seventy-two married men completed end-of-day diaries in which they rated their mood...
10.
Stone A, Neale J, Cox D, Napoli A, Valdimarsdottir H
Health Psychol . 1994 Sep; 13(5):440-6. PMID: 7805639
To examine a hypothesized link between daily stressful events and secretory immunoglobulin A (sIgA) antibody, 96 adults from the community completed daily event questionnaires and gave daily saliva samples for...