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D Ruggero

Explore the profile of D Ruggero including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 386
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Recent Articles
1.
Hsieh A, Truitt M, Ruggero D
Br J Cancer . 2011 Jul; 105(3):329-36. PMID: 21772331
The AKT signalling pathway is a major regulator of protein synthesis that impinges on multiple cellular processes frequently altered in cancer, such as proliferation, cell growth, survival, and angiogenesis. AKT...
2.
Rego E, Ruggero D, Tribioli C, Cattoretti G, Kogan S, Redner R, et al.
Oncogene . 2005 Dec; 25(13):1974-9. PMID: 16331271
Recurrent chromosomal translocations involving the RAR alpha locus on chromosome 17 are the hallmark of acute promyelocytic leukemia (APL). The RAR alpha gene fuses to variable partners (PML, PLZF, NPM,...
3.
Ruggero D, Wang Z, Pandolfi P
Bioessays . 2000 Aug; 22(9):827-35. PMID: 10944585
PML, the gene associated with acute promyelocytic leukemia (APL); PML, the target of numerous viral agents; PML, the growth suppressor; PML, the mediator of multiple apoptotic pathways; PML, the tumor...
4.
Zhong S, Salomoni P, Ronchetti S, Guo A, Ruggero D, Pandolfi P
J Exp Med . 2000 Feb; 191(4):631-40. PMID: 10684855
The promyelocytic leukemia protein (PML) gene of acute promyelocytic leukemia (APL) encodes a cell growth and tumor suppressor essential for multiple apoptotic signals. Daxx was identified as a molecule important...
5.
Condo I, Ciammaruconi A, Benelli D, Ruggero D, Londei P
Mol Microbiol . 1999 Nov; 34(2):377-84. PMID: 10564480
In this work, we have studied the in vitro translational features of a bicistronic mRNA of the extremely thermophilic Archaeon Sulfolobus solfataricus, with the aim of determining the nature of...
6.
Wang Z, Ruggero D, Ronchetti S, Zhong S, Gaboli M, Rivi R, et al.
Nat Genet . 1998 Nov; 20(3):266-72. PMID: 9806545
The PML gene of acute promyelocytic leukaemia (APL) encodes a cell growth and tumour suppressor, however, the mechanisms by which PML suppresses tumorigenesis are poorly understood. We show here that...
7.
Condo I, Ruggero D, Reinhardt R, Londei P
Mol Microbiol . 1998 Sep; 29(3):775-85. PMID: 9723917
The chaperonins are high-molecular-weight protein complexes having a characteristic double-ring toroidal shape; they are thought to aid the folding of denatured or newly synthesized polypeptides. These proteins exist as two...
8.
Ruggero D, Ciammaruconi A, Londei P
EMBO J . 1998 Jun; 17(12):3471-7. PMID: 9628882
The 60 kDa molecular chaperones (chaperonins) are high molecular weight protein complexes having a characteristic double-ring toroidal shape; they are thought to aid the folding of denatured or newly synthesized...
9.
Ruggero D, Londei P
J Bacteriol . 1996 Jun; 178(11):3396-8. PMID: 8655531
Hybrid ribosomes obtained by mixing the ribosomal subunits of the extremely thermophilic archaea Sulfolobus solfataricus and Desulfurococcus mobilis were tested for their sensitivity to selected antibiotics. It is shown that...
10.
Bandini G, Ricci P, Ruggero D, Cantore M, Visani G, Tura S
Tumori . 1982 Oct; 68(5):427-30. PMID: 6960590
Twelve adult patients with acute lymphoblastic leukemia (ALL) received lithium carbonate, 300 mg, three times a day during induction treatment. They were compared to 12 similar patients consecutively treated with...