D Robert E Abayasekara
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Explore the profile of D Robert E Abayasekara including associated specialties, affiliations and a list of published articles.
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9
Citations
250
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Recent Articles
1.
Marei W, Abayasekara D, Wathes D, Fouladi-Nashta A
Reprod Biomed Online
. 2014 Jan;
28(3):388-400.
PMID: 24447957
Prostaglandin E2 (PGE2) is an autocrine/paracrine factor which mediates gonadotrophin (Gn) stimulation of cumulus expansion and oocyte maturation in rodents. Its role in bovine oocyte maturation is less characterized. This...
2.
Cheng Z, Abayasekara D, Ward F, Preece D, Raheem K, Wathes D
Anim Reprod Sci
. 2013 Nov;
143(1-4):38-47.
PMID: 24287151
Consumption of n-3 polyunsaturated fatty acids (PUFAs) is considered beneficial to health but effects on fertility remain uncertain. This study investigated the effect of n-3 PUFA supplementation on endometrial prostaglandin...
3.
Sheldrick E, Derecka K, Marshall E, Chin E, Hodges L, Wathes D, et al.
Biochem J
. 2007 May;
406(1):175-83.
PMID: 17516915
Arachidonic acid is a potential paracrine agent released by the uterine endometrial epithelium to induce PTGS2 [PG (prostaglandin)-endoperoxide synthase 2] in the stroma. In the present study, bovine endometrial stromal...
4.
Wathes D, Abayasekara D, Aitken R
Biol Reprod
. 2007 Apr;
77(2):190-201.
PMID: 17442851
In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs) far exceeds nutritional requirements. The ratio of n-6 to n-3 PUFAs is generally >10:1 whereas on a primitive human...
5.
Jonas K, Chandras C, Abayasekara D, Michael A
Endocrinology
. 2006 Sep;
147(12):5865-72.
PMID: 16959838
11beta-hydroxysteroid dehydrogenase (11betaHSD) enzymes regulate glucocorticoid availability in target tissues. 11betaHSD1 is the predominant isoenzyme expressed and active in human granulosa-lutein (hGL) cells. This study investigated the effects of pharmacological...
6.
Cheng Z, Abayasekara D, Wathes D
Biochim Biophys Acta
. 2005 Sep;
1736(2):128-35.
PMID: 16140575
Linoleic acid (LA, 18:2n-6) has variously been found to increase or inhibit synthesis of 2-series prostaglandins (PGs), derived from arachidonic acid (AA, 20:4n-6). gamma-linolenic acid (GLA, 18:3n-6) containing oils are...
7.
Elmes M, Tew P, Cheng Z, Kirkup S, Abayasekara D, Calder P, et al.
Biochim Biophys Acta
. 2004 Nov;
1686(1-2):139-47.
PMID: 15522830
Linoleic acid (18:2n-6) is metabolised to arachidonic acid (20:4n-6), the precursor for 2-series prostaglandins (PGs). Increased consumption of 18:2n-6 during pregnancy may thus modify PG synthesis during labour. We have...
8.
Chandras C, Ragoobir J, Barrett G, Bruckdorfer K, Graham A, Abayasekara D, et al.
Mol Cell Endocrinol
. 2004 Jul;
222(1-2):1-8.
PMID: 15249120
In human granulosa-lutein cells, high-density lipoproteins (HDL) can stimulate progesterone synthesis. The objective of the present study was to establish whether prostaglandins (PGs) participate in the steroidogenic response to HDL....
9.
Thurston L, Jonas K, Abayasekara D, Michael A
Biol Reprod
. 2003 Feb;
68(6):2157-63.
PMID: 12606327
In the ovary, cortisol is oxidized to cortisone by 11beta-hydroxysteroid dehydrogenase (11betaHSD). The present study investigated whether follicular fluid (FF) from large antral follicles and spontaneous ovarian cysts, isolated from...