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D R Houck

Explore the profile of D R Houck including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 88
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Recent Articles
1.
Wanner R, Spielmann P, Stroka D, Camenisch G, Camenisch I, Scheid A, et al.
Blood . 2000 Aug; 96(4):1558-65. PMID: 10942406
Induction of erythropoietin (Epo) expression under hypoxic conditions is mediated by the heterodimeric hypoxia-inducible factor (HIF)-1. Following binding to the 3' hypoxia-response element (HRE) of the Epo gene, HIF-1 markedly...
2.
Unkefer C, Houck D, Britt B, Sosnick T, Hanners J
Methods Enzymol . 1995 Jan; 258:227-35. PMID: 8524153
No abstract available.
3.
Alvarez M, Houck D, White C, Brownell J, Bobko M, Rodger C, et al.
J Antibiot (Tokyo) . 1994 Nov; 47(11):1195-201. PMID: 8002381
Two new peptides, a diketopiperazine of N-methyltyrosine (1) and a tetrapeptide containing N-methyltyrosine (2), were isolated from an actinomycete strain Streptomyces griseus. These compounds inhibit the enzyme calpain in the...
4.
Brownell J, Earley W, Kunec E, Morgan B, Olyslager B, Wahl R, et al.
Arch Biochem Biophys . 1994 Oct; 314(1):120-5. PMID: 7944383
A novel radiometric assay was developed for human fibroblast collagenase (matrix metalloproteinase-1, MMP-1), stromelysin (MMP-3), and their recombinant catalytic domains. Using this assay we were able to compare the native...
5.
Popp J, Musza L, Barrow C, Rudewicz P, Houck D
J Antibiot (Tokyo) . 1994 Apr; 47(4):411-9. PMID: 7515039
WIN 64821 (1) is a substance P (SP) antagonist isolated from a fungal culture (Aspergillus sp., SC319). It is a symmetrical dimer biosynthesized from four aromatic amino acid molecules: each...
6.
Sedlock D, Barrow C, Brownell J, Hong A, Gillum A, Houck D
J Antibiot (Tokyo) . 1994 Apr; 47(4):391-8. PMID: 7515037
WIN 64821, a nonpeptide neurokinin antagonist, was isolated from a strain of Aspergillus sp., SC319. The compound was produced in different fermentation media with greatest yields observed when the culture...
7.
Smidt C, Unkefer C, Houck D, Rucker R
Proc Soc Exp Biol Med . 1991 May; 197(1):27-31. PMID: 1850522
Pyrroloquinoline quinone (PQQ) functions as a cofactor for prokaryotic oxidoreductases, such as methanol dehydrogenase and membrane-bound glucose dehydrogenase. In animals fed chemically defined diets, PQQ improves reproductive outcome and neonatal...
8.
Mocek U, Chen L, Keller P, Houck D, Beale J, Floss H
J Antibiot (Tokyo) . 1989 Nov; 42(11):1643-8. PMID: 2584148
The 1H and 13C NMR spectra of nosiheptide have been assigned by use of 2D NMR techniques on unlabeled samples and biosynthetically multiple-labeled samples from stable isotope feeding experiments.
9.
Houck D, Hanners J, Unkefer C, van Kleef M, Duine J
Antonie Van Leeuwenhoek . 1989 May; 56(1):93-101. PMID: 2549867
Using 13C labeling and NMR spectroscopy we have determined biosynthetic precursors of pyrroloquinoline quinone (PQQ) in two closely related serine-type methylotrophs, Methylobacterium AM1 and Hyphomicrobium X. Analysis of the 13C-labeling...
10.
Houck D, Ondeyka J, ZINK D, Inamine E, Goetz M, Hensens O
J Antibiot (Tokyo) . 1988 Jul; 41(7):882-91. PMID: 3417563
Feeding of 14C-labeled amino acids to resting cells of Aspergillus alliaceus strongly supported the intuitive hypothesis that asperlicin is biosynthesized from tryptophan, anthranilate and leucine. The resting cell system was...