D R Dunbar
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Explore the profile of D R Dunbar including associated specialties, affiliations and a list of published articles.
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13
Citations
369
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Recent Articles
1.
Qiu J, Dunbar D, Noble J, Cairns C, Carter R, Kelly V, et al.
J Neuroendocrinol
. 2015 Nov;
28(1).
PMID: 26563879
Mice deficient in the glucocorticoid-regenerating enzyme 11β-HSD1 resist age-related spatial memory impairment. To investigate the mechanisms and pathways involved, we used microarrays to identify differentially expressed hippocampal genes that associate...
2.
Rog-Zielinska E, Craig M, Manning J, Richardson R, Gowans G, Dunbar D, et al.
Cell Death Differ
. 2014 Nov;
22(7):1106-16.
PMID: 25361084
Glucocorticoid levels rise dramatically in late gestation to mature foetal organs in readiness for postnatal life. Immature heart function may compromise survival. Cardiomyocyte glucocorticoid receptor (GR) is required for the...
3.
Khulan B, Manning J, Dunbar D, Seckl J, Raikkonen K, Eriksson J, et al.
Transl Psychiatry
. 2014 Sep;
4:e448.
PMID: 25247593
Early-life stress (ELS) is known to be associated with an increased risk of neuropsychiatric and cardiometabolic disease in later life. One of the potential mechanisms underpinning this is through effects...
4.
Semprini S, Troup T, Kotelevtseva N, King K, Davis J, Mullins L, et al.
Nucleic Acids Res
. 2007 Feb;
35(5):1402-10.
PMID: 17284462
Cre is widely used for DNA tailoring and, in combination with recombineering techniques, to modify BAC/PAC sequences for generating transgenic animals. However, mammalian genomes contain recombinase recognition sites (cryptic loxP...
5.
Thomson P, Wray N, Thomson A, Dunbar D, Grassie M, Condie A, et al.
Mol Psychiatry
. 2004 Sep;
10(5):470-8.
PMID: 15452587
GPR50 is an orphan G protein-coupled receptor (GPCR) located on Xq28, a region previously implicated in multiple genetic studies of bipolar affective disorder (BPAD). Allele frequencies of three polymorphisms in...
6.
Morrow J, Collie I, Dunbar D, WALKER G, Shahid M, Hill D
FEBS Lett
. 1998 Dec;
439(3):334-40.
PMID: 9845349
Neurotransmitter transport systems are major targets for therapeutic alterations in synaptic function. We have cloned and sequenced a cDNA encoding the human type 2 glycine transporter GlyT2 from human brain...
7.
Holt I, Dunbar D, Jacobs H
Hum Mol Genet
. 1997 Aug;
6(8):1251-60.
PMID: 9259270
We have studied the dynamics of mitochondrial DNA maintenance and segregation in human cells using serial cybrid transfer of partially duplicated mitochondrial DNA, from a mitochondrial myopathy patient, to two...
8.
Dunbar D, Shibasaki Y, Dobbie L, Andersson B, Brookes A
Cytogenet Cell Genet
. 1997 Jan;
78(1):21-4.
PMID: 9345899
Using human and bovine short cDNA sequences as probes we screened human cosmid and P1 libraries for components of the complex I multi-subunit enzyme of oxidative phosphorylation. We isolated genomic...
9.
Dunbar D, Moonie P, Zeviani M, Holt I
Hum Mol Genet
. 1996 Jan;
5(1):123-29.
PMID: 8789449
143B.206 rho degrees cells were repopulated with mitochondria from a MELAS patient harbouring a mixture of 3243G:C and 3243A:T mitochondrial DNA. A number of biochemical assays were performed on selected...
10.
Dunbar D, Moonie P, Jacobs H, Holt I
Proc Natl Acad Sci U S A
. 1995 Jul;
92(14):6562-6.
PMID: 7604033
After the introduction of mitochondria with a mixture of mutant and wild-type mitochondrial DNA (mtDNA) into a human rho degree cell line (143B.206), Yoneda et al. [Yoneda, M., Chomyn, A.,...