D O Haskard
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Explore the profile of D O Haskard including associated specialties, affiliations and a list of published articles.
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155
Citations
2789
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Recent Articles
1.
Khan E, Ambrose N, Ahnstrom J, Kiprianos A, Stanford M, Eleftheriou D, et al.
Sci Rep
. 2016 Dec;
6:38104.
PMID: 27924945
Thrombosis is common in Behçet's Syndrome (BS), and there is a need for better biomarkers for risk assessment. As microparticles expressing Tissue Factor (TF) can contribute to thrombosis in preclinical...
2.
Ambrose N, Khan E, Ravindran R, Lightstone L, Abraham S, Botto M, et al.
Clin Exp Immunol
. 2015 May;
181(3):427-33.
PMID: 25982097
The mechanisms underlying the exaggerated inflammatory response in Behçet's syndrome (BS) remain poorly understood. We investigated the response of CD14(+) blood monocytes to interferon (IFN)-γ, focusing on the chemokine CXCL10....
3.
Thornton C, Al-Rashed F, Calay D, Birdsey G, Bauer A, Mylroie H, et al.
Ann Rheum Dis
. 2015 Jan;
75(2):439-48.
PMID: 25575725
Aims: Premature cardiovascular events complicate chronic inflammatory conditions. Low-dose weekly methotrexate (MTX), the most widely used disease-modifying drug for rheumatoid arthritis (RA), reduces disease-associated cardiovascular mortality. MTX increases intracellular accumulation...
4.
Lightman S, Taylor S, Bunce C, Longhurst H, Lynn W, Moots R, et al.
Ann Rheum Dis
. 2014 Oct;
74(6):1138-44.
PMID: 25269831
Objective: To determine whether the addition of 26 weeks of subcutaneous peginterferon-α-2b could reduce the requirement for systemic corticosteroids and conventional immunosuppressive medication in patients with Behçet's disease (BD). Methods:...
5.
Barbarulo A, Iansante V, Chaidos A, Naresh K, Rahemtulla A, Franzoso G, et al.
Oncogene
. 2012 Oct;
32(36):4231-42.
PMID: 23045269
Regulation of cell survival is a key part of the pathogenesis of multiple myeloma (MM). Jun N-terminal kinase (JNK) signaling has been implicated in MM pathogenesis, but its function is...
6.
Landis R, Evans B, Chaturvedi N, Haskard D
Diabetologia
. 2010 Apr;
53(7):1537-8.
PMID: 20419448
No abstract available.
7.
Hamdulay S, Cheent K, Ghosh C, Stocks J, Ghosh S, Haskard D
Rheumatology (Oxford)
. 2008 Jun;
47(8):1231-4.
PMID: 18550639
Objective: Intestinal Behçet's Syndrome (BS) is a difficult diagnosis to establish. We describe the use of wireless capsule endoscopy (WCE) in the investigation of 11 patients with suspected intestinal BS....
8.
Evans B, Haskard D, Finch J, Hambleton I, Landis R, Taylor K
J Thorac Cardiovasc Surg
. 2008 May;
135(5):999-1006.
PMID: 18455576
Objective: Extravascular trafficking of leukocytes into organs is thought to play a major role in the pathophysiologic mechanisms of the inflammatory response to cardiopulmonary bypass, yet leukocyte extravasation is difficult...
9.
Ali F, Hamdulay S, Kinderlerer A, Boyle J, Lidington E, Yamaguchi T, et al.
J Thromb Haemost
. 2007 Oct;
5(12):2537-46.
PMID: 17927807
Background: Heme oxygenase-1 (HO-1), by exerting anti-inflammatory, antiproliferative, antiapoptotic and antioxidant effects in the vasculature, protects against atherosclerosis and post-transplant vasculopathy. We noted the overlap between the effects of HO-1...
10.
Hepburn A, Mason J, Wang S, Shepherd C, Florey O, Haskard D, et al.
Clin Exp Immunol
. 2006 Sep;
146(1):133-45.
PMID: 16968408
Abnormal clearance by the mononuclear phagocytic system of immune complexes (IC) is important in the pathogenesis of systemic lupus erythematosus (SLE). We have developed an in vitro model to investigate...