D M Reynolds
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Explore the profile of D M Reynolds including associated specialties, affiliations and a list of published articles.
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42
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1217
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Recent Articles
11.
Reynolds D, Falk C, Li A, King B, Kamath P, Huston 3rd J, et al.
Am J Hum Genet
. 2000 Nov;
67(6):1598-604.
PMID: 11047756
Polycystic liver disease (PCLD) is characterized by the growth of fluid-filled cysts of biliary epithelial origin in the liver. Although the disease is often asymptomatic, it can, when severe, lead...
12.
Kumar R, Reynolds D, Shevchenko A, Goldstone S, Dalton S
Curr Biol
. 2000 Aug;
10(15):896-906.
PMID: 10959837
Background: The 'CLB2 cluster' in Saccharomyces cerevisiae consists of approximately 33 genes whose transcription peaks in late G2/early M phase of the cell cycle. Many of these genes are required...
13.
Reynolds D, Hayashi T, Cai Y, Veldhuisen B, Watnick T, Lens X, et al.
J Am Soc Nephrol
. 1999 Nov;
10(11):2342-51.
PMID: 10541293
It is estimated that approximately 15% of families with autosomal dominant polycystic kidney disease (ADPKD) have mutations in PKD2. Identification of these mutations is central to identifying functionally important regions...
14.
Wu G, Hayashi T, Park J, Dixit M, Reynolds D, Li L, et al.
Genomics
. 1999 Jan;
54(3):564-8.
PMID: 9878261
Mutations in PKD2 cause autosomal dominant kidney disease (ADPKD). Polycystin-2, the PKD2 gene product, is an integral membrane glycoprotein of unknown function. We have identified PKD2L, another member of the...
15.
Wu G, DAgati V, Cai Y, Markowitz G, Park J, Reynolds D, et al.
Cell
. 1998 May;
93(2):177-88.
PMID: 9568711
Germline mutations in PKD2 cause autosomal dominant polycystic kidney disease. We have introduced a mutant exon 1 in tandem with the wild-type exon 1 at the mouse Pkd2 locus. This...
16.
Reynolds D, Hazle J, Johnston D, Charnsangavej C
Med Phys
. 1998 Mar;
25(2):176-82.
PMID: 9507477
Helical x-ray computed tomography (hCT) is the volume acquisition of image data in which the data set represents a series of projections obtained in a helical spatial distribution. Data acquisition...
17.
Viribay M, Hayashi T, Telleria D, Mochizuki T, Reynolds D, Alonso R, et al.
Hum Genet
. 1997 Dec;
101(2):229-34.
PMID: 9402976
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most frequent inherited disorders. The majority of cases are due to mutation of the PKD1 gene, on 16p13.3, while in...
18.
Wu G, Mochizuki T, Le T, Cai Y, Hayashi T, Reynolds D, et al.
Genomics
. 1997 Oct;
45(1):220-3.
PMID: 9339380
The gene responsible for the second form of autosomal dominant polycystic kidney disease, PKD2, has recently been identified. We now describe the cloning, genomic localization, cDNA sequence, and expression analysis...
19.
Veldhuisen B, Saris J, de Haij S, Hayashi T, Reynolds D, Mochizuki T, et al.
Am J Hum Genet
. 1997 Oct;
61(3):547-55.
PMID: 9326320
Recently the second gene for autosomal dominant polycystic kidney disease (ADPKD), located on chromosome 4q21-q22, has been cloned and characterized. The gene encodes an integral membrane protein, polycystin-2, that shows...
20.
Hayashi T, Mochizuki T, Reynolds D, Wu G, Cai Y, Somlo S
Genomics
. 1997 Aug;
44(1):131-6.
PMID: 9286709
PKD2, the gene defective in the second form of autosomal dominant polycystic kidney disease (ADPKD), has been identified by positional cloning and found to encode an integral membrane protein with...