D M Michaelson
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Explore the profile of D M Michaelson including associated specialties, affiliations and a list of published articles.
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92
Citations
772
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Recent Articles
1.
Schmukler E, Michaelson D, Pinkas-Kramarski R
Mol Neurobiol
. 2018 Jan;
55(8):6863-6880.
PMID: 29353455
Since its discovery as a genetic risk factor for Alzheimer's disease, the APOE4 allele has been linked to the majority of the pathological findings associated with the disease progression. These...
2.
Barak B, Shvarts-Serebro I, Modai S, Gilam A, Okun E, Michaelson D, et al.
Transl Psychiatry
. 2013 Sep;
3:e304.
PMID: 24022509
Alzheimer's disease (AD) is the most common form of dementia in the elderly. Although there are no drugs that modify the disease process, exposure to an enriched environment (EE) can...
3.
Karussis D, Michaelson D, Grigoriadis N, Korezyn A, Mizrachi-Koll R, Chapman S, et al.
Mult Scler
. 2003 Oct;
9(5):476-80.
PMID: 14582773
Experimental autoimmune encephalomyelitis (EAE) was found to have a chronic and significantly worse course in apolipoprotein-E (apoE) deficient female mice when compared with matched controls. Disease measures compared included incidence...
4.
Ezra Y, Oron L, Moskovich L, Roses A, Beni S, Shohami E, et al.
Neuroscience
. 2003 Oct;
121(2):315-25.
PMID: 14521991
Apolipoprotein E (apoE4) and head trauma are important genetic and environmental risk factors for Alzheimer's disease. Furthermore, apoE4 increases both the acute and chronic consequences of head trauma. The latter...
5.
Chapman J, Korczyn A, Karussis D, Michaelson D
Neurology
. 2001 Oct;
57(8):1482-5.
PMID: 11673593
APOE genotype influences the age at onset of some neurodegenerative diseases such as AD and the rate of progression in others such as MS. The authors hypothesize that APOE genotype...
6.
Bornstein N, Aronovich B, Korczyn A, Shavit S, Michaelson D, Chapman J
Neurology
. 2001 Feb;
56(4):529-30.
PMID: 11222800
Cerebral necrosis following stroke exposes brain antigens to the immune system, potentially initiating an antibody response. The authors measured levels of antibodies to specific neuronal antigens, neurofilaments (NF), and a...
7.
Fisher A, Michaelson D, Brandeis R, Haring R, Chapman S, Pittel Z
Ann N Y Acad Sci
. 2001 Feb;
920:315-20.
PMID: 11193170
A cholinergic hypofunction in Alzheimer's disease (AD) may lead to formation of beta-amyloids that might impair the coupling of M1 muscarinic ACh receptors (mAChRs) with G proteins. This disruption in...
8.
Chapman J, Vinokurov S, Achiron A, Karussis D, Mitosek-Szewczyk K, Birnbaum M, et al.
Neurology
. 2001 Feb;
56(3):312-6.
PMID: 11171894
Background And Objective: The authors recently reported that the APOE epsilon4 allele is associated with significantly greater progression of disability in a 2-year follow-up of patients with MS. In this...
9.
Sabo T, Lomnitski L, Nyska A, Beni S, Maronpot R, Shohami E, et al.
Neuroscience
. 2000 Dec;
101(4):879-84.
PMID: 11113336
Apolipoprotein E, the major brain lipid-binding protein, is expressed in humans as three common isoforms (E2, E3 and E4). Previous studies revealed that the allele apolipoprotein E4 is a major...
10.
Leloup C, Michaelson D, Fisher A, Hartmann T, Beyreuther K, Stein R
Cell Death Differ
. 2000 Oct;
7(9):825-33.
PMID: 11042677
When PC12 cells are deprived of trophic support they undergo apoptosis. We have previously shown that survival of trophic factor-deprived PC12M1 cells can be promoted by activation of the G...