D M Lyerly
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Explore the profile of D M Lyerly including associated specialties, affiliations and a list of published articles.
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57
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1656
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Recent Articles
1.
Archbald-Pannone L, Boone J, Carman R, Lyerly D, Guerrant R
J Hosp Infect
. 2014 Sep;
88(4):218-21.
PMID: 25228227
Intestinal inflammation was evaluated using faecal lactoferrin and ribotype in 196 hospitalized adults with Clostridium difficile infection to determine the impact of ribotype 027 in long-term care facilities (LTCFs). LTCF...
2.
Boone J, Archbald-Pannone L, Wickham K, Carman R, Guerrant R, Franck C, et al.
Eur J Clin Microbiol Infect Dis
. 2014 Jan;
33(6):1045-51.
PMID: 24449345
We evaluated clinical and diagnostic indicators of severe C. difficile infection (CDI) and their association with poor clinical outcome. A total of 210 patients positive according to PCR (toxin B:...
3.
Boone J, DiPersio J, Tan M, Salstrom S, Wickham K, Carman R, et al.
Eur J Clin Microbiol Infect Dis
. 2013 Jun;
32(12):1517-23.
PMID: 23771554
We evaluated blood and fecal biomarkers as indicators of severity in symptomatic patients with confirmed Clostridium difficile infection (CDI). Recruitment included patients with CDI based on clinical symptoms and supporting...
4.
Carman R, Wickham K, Chen L, Lawrence A, Boone J, Wilkins T, et al.
J Clin Microbiol
. 2012 Feb;
50(4):1425-6.
PMID: 22301027
gluD was highly conserved and glutamate dehydrogenase (GDH) was readily expressed in vitro by all 77 Clostridium difficile ribotypes assayed. All ribotypes, including ARL 002, ARL 027, and ARL 106,...
5.
Boone J, Goodykoontz M, Rhodes S, Price K, Smith J, Gearhart K, et al.
Eur J Clin Microbiol Infect Dis
. 2011 Dec;
31(7):1551-9.
PMID: 22167256
We evaluated Clostridium difficile prevalence rates in 2,807 clinically indicated stool specimens stratified by inpatient (IP), nursing home patient (NH), outpatient (OP), age, gender, and specimen consistency using bacterial culture,...
6.
Multicenter evaluation of a new screening test that detects Clostridium difficile in fecal specimens
Zheng L, Keller S, Lyerly D, Carman R, Genheimer C, Gleaves C, et al.
J Clin Microbiol
. 2004 Aug;
42(8):3837-40.
PMID: 15297543
Clostridium difficile causes approximately 25% of nosocomial antibiotic-associated diarrheas and most cases of pseudomembranous colitis. We evaluated C. DIFF CHEK, a new screening test that detects glutamate dehydrogenase of C....
7.
Genetic characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates by PCR
Moncrief J, Zheng L, Neville L, Lyerly D
J Clin Microbiol
. 2000 Aug;
38(8):3072-5.
PMID: 10921980
Toxin-specific enzyme immunoassays, cytotoxicity assays, and PCR were used to analyze 48 toxin A-negative, toxin B-positive Clostridium difficile isolates from various geographical sites around the world. All the isolates were...
8.
Pavliakova D, Moncrief J, Lyerly D, Schiffman G, Bryla D, Robbins J, et al.
Infect Immun
. 2000 Mar;
68(4):2161-6.
PMID: 10722615
Unlike the native protein, a nontoxic peptide (repeating unit of the native toxin designated rARU) from Clostridium difficile toxin A (CDTA) afforded an antigen that could be bound covalently to...
9.
Kato H, Kato N, Katow S, MAEGAWA T, Nakamura S, Lyerly D
FEMS Microbiol Lett
. 1999 Jul;
175(2):197-203.
PMID: 10386368
The repeating sequences of the toxin A gene from toxin A-negative, toxin B-positive (toxin A-, toxin B+) strains of Clostridium difficile which were isolated in geographically separated facilities in Japan...
10.
Boone J, Wilkins T, Nash T, Brandon J, Macias E, Jerris R, et al.
J Clin Microbiol
. 1999 Feb;
37(3):611-4.
PMID: 9986821
A Giardia lamblia antigen detected by the TechLab Giardia Test (TechLab, Inc., Blacksburg, Va.) and the Alexon ProSpecT Giardia microplate assay (Alexon, Inc., Sunnyvale, Calif.) was purified by immunoaffinity chromatography...