D M Kube
Overview
Explore the profile of D M Kube including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
279
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Recent Articles
1.
Mah C, Qing K, Khuntirat B, Ponnazhagan S, Wang X, Kube D, et al.
J Virol
. 1998 Nov;
72(12):9835-43.
PMID: 9811719
Adeno-associated virus type 2 (AAV), a single-stranded, DNA-containing, nonpathogenic human parvovirus, has gained attention as a potentially useful vector for human gene therapy. However, the transduction efficiency of AAV vectors...
2.
Wang X, Khuntirat B, Qing K, Ponnazhagan S, Kube D, Zhou S, et al.
J Virol
. 1998 Jun;
72(7):5472-80.
PMID: 9621003
The pSub201-pAAV/Ad plasmid cotransfection system was developed to eliminate homologous recombination which leads to generation of the wild-type (wt) adeno-associated virus type 2 (AAV) during recombinant vector production. The extent...
3.
Qing K, Khuntirat B, Mah C, Kube D, Wang X, Ponnazhagan S, et al.
J Virol
. 1998 Jan;
72(2):1593-9.
PMID: 9445062
Although the adeno-associated virus type 2 (AAV)-based vector system has gained attention as a potentially useful alternative to the more commonly used retroviral and adenoviral vectors for human gene therapy,...
4.
Ponnazhagan S, Mukherjee P, Wang X, Qing K, Kube D, Mah C, et al.
J Virol
. 1997 Oct;
71(11):8262-7.
PMID: 9343178
Although the adeno-associated virus type 2 (AAV) is known to possess a broad host range that transcends the species barrier, we suggested in an earlier study that AAV infection of...
5.
Qing K, Wang X, Kube D, Ponnazhagan S, Bajpai A, Srivastava A
Proc Natl Acad Sci U S A
. 1997 Oct;
94(20):10879-84.
PMID: 9380728
The adeno-associated virus 2 (AAV), a single-stranded DNA-containing, nonpathogenic human parvovirus, has gained attention as a potentially useful vector for human gene therapy. However, the single-stranded nature of the viral...
6.
Kube D, Ponnazhagan S, Srivastava A
J Virol
. 1997 Oct;
71(10):7361-71.
PMID: 9311814
The adeno-associated virus type 2 (AAV) arrests the growth of primary human fibroblasts in vitro at high particle-to-cell ratios. To test the role of AAV gene expression in the observed...
7.
Kube D, Srivastava A
Nucleic Acids Res
. 1997 Aug;
25(16):3375-6.
PMID: 9241256
Titers of wild-type and recombinant adeno-associated viruses are routinely determined by DNA slot blot analysis. The binding of viral DNA to nylon membranes was found to be inhibited by magnesium...
8.
Eckman E, Cotton C, Kube D, DAVIS P
Am J Physiol
. 1995 Nov;
269(5 Pt 1):L625-30.
PMID: 7491981
Over 90% of untreated CFTR S489X homozygous (CF) mutant mice reportedly die of intestinal obstruction by 40 days of age, significantly limiting their usefulness as a model for the human...