Alpha 2.0
Login Register
» Authors » D Liaw

D Liaw

Explore the profile of D Liaw including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 2707
Followers 0
Related Specialties
Genetics
Cell Biology
Molecular Biology
Top 10 Co-Authors
R Parsons
C Eng
P L Dahia
J Li
D J Marsh
Z Zheng
S Bose
R J GORLIN
S I Wang
J M Bonnetblanc
Published In
Nat Genet
Science
Pathobiology
Hum Mol Genet
Am J Med Genet
Affiliations
Soon will be listed here.
Recent Articles
1.
PTEN expression causes feedback upregulation of insulin receptor substrate 2
Simpson L, Li J, Liaw D, Hennessy I, Oliner J, Christians F, et al.
Mol Cell Biol . 2001 May; 21(12):3947-58. PMID: 11359902
PTEN is a tumor suppressor that antagonizes phosphatidylinositol-3 kinase (PI3K) by dephosphorylating the D3 position of phosphatidylinositol (3,4,5)-triphosphate (PtdIns-3,4,5-P3). Given the importance of PTEN in regulating PtdIns-3,4,5-P3 levels, we used...
2.
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
Marsh D, Coulon V, Lunetta K, Rocca-Serra P, Dahia P, Zheng Z, et al.
Hum Mol Genet . 1998 Apr; 7(3):507-15. PMID: 9467011
The tumour suppressor gene PTEN , which maps to 10q23.3 and encodes a 403 amino acid dual specificity phosphatase (protein tyrosine phosphatase; PTPase), was shown recently to play a broad...
3.
Deletion of PTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease
Arch E, Goodman B, Van Wesep R, Liaw D, Clarke K, Parsons R, et al.
Am J Med Genet . 1997 Sep; 71(4):489-93. PMID: 9286463
We report on an 18-month-old boy with an interstitial deletion at 10q23.2-q24.1. This region includes the PTEN gene, mutations of which have been reported to cause Cowden disease. Our patient...
4.
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
Marsh D, Dahia P, Zheng Z, Liaw D, Parsons R, GORLIN R, et al.
Nat Genet . 1997 Aug; 16(4):333-4. PMID: 9241266
No abstract available.
5.
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
Liaw D, Marsh D, Li J, Dahia P, Wang S, Zheng Z, et al.
Nat Genet . 1997 May; 16(1):64-7. PMID: 9140396
Cowden disease (CD) is an autosomal dominant cancer predisposition syndrome associated with an elevated risk for tumours of the breast, thyroid and skin. Lhermitte-Duclos disease (LDD) cosegregates with a subset...
6.
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang S, et al.
Science . 1997 Mar; 275(5308):1943-7. PMID: 9072974
Mapping of homozygous deletions on human chromosome 10q23 has led to the isolation of a candidate tumor suppressor gene, PTEN, that appears to be mutated at considerable frequency in human...
7.
Comparative analysis of smooth muscle isoactin gene expression in normal and neoplastic tissues
Brittingham J, Liaw D, Liddell R, McHugh M, McCue P, McHugh K
Pathobiology . 1997 Jan; 65(3):113-22. PMID: 9309777
Monoclonal antibodies derived from the actin multigene family are routinely used as an adjunct to morphologic diagnoses of smooth muscle tumors. Northern blot analysis was performed on 60 surgical resections...