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D L Rickett

Explore the profile of D L Rickett including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 11
Citations 105
Followers 0
Related Specialties
Pharmacology
Toxicology
Molecular Biology
Top 10 Co-Authors
E X Albuquerque
Y Aracava
A Akaike
K P Shaw
S S Deshpande
G J Pascuzzo
E T Beers
K S Rao
A Brossi
S R Ikeda
Published In
Mol Pharmacol
Fundam Appl Toxicol
J Pharmacol Exp Ther
Toxicol Appl Pharmacol
Ann N Y Acad Sci
Affiliations
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Recent Articles
1.
Neurophysiological concomitants of soman-induced respiratory depression in awake, behaving guinea pigs
Chang F, Foster R, Beers E, Rickett D, FILBERT M
Toxicol Appl Pharmacol . 1990 Feb; 102(2):233-50. PMID: 2300968
Soman-induced respiratory failure was investigated in awake, behaving guinea pigs chronically instrumented to allow concurrent recordings of medullary respiratory-related unit (RRU) activity, diaphragm electromyogram (DEMG), and electrocorticogram. Responses to soman...
2.
The molecular basis of anticholinesterase actions on nicotinic and glutamatergic synapses
Aracava Y, Deshpande S, Rickett D, Brossi A, Schonenberger B, Albuquerque E
Ann N Y Acad Sci . 1987 Jan; 505:226-55. PMID: 2446549
No abstract available.
3.
Noncompetitive blockade of the nicotinic acetylcholine receptor-ion channel complex by an irreversible cholinesterase inhibitor
Rao K, Aracava Y, Rickett D, Albuquerque E
J Pharmacol Exp Ther . 1987 Jan; 240(1):337-44. PMID: 2433427
Interactions of O-ethyl S-[2-(diisopropylamino)ethyl]methylphosphonothioate (VX), an irreversible, organophosphorus, anticholinesterase (anti-ChE) agent, with the nicotinic acetylcholine receptor-ion channel complex (AChR) of the frog Rana pipiens were investigated using electrophysiological techniques. At...
4.
Organophosphate and carbamate compounds have pre- and postjunctional effects at the insect glutamatergic synapse
Idriss M, Aguayo L, Rickett D, Albuquerque E
J Pharmacol Exp Ther . 1986 Oct; 239(1):279-85. PMID: 2876093
The effects of the organophosphate compounds diisopropylfluorophosphate (DFP), dimethylphosphoramidocyanidic acid ethyl ester (tabun), O-ethyl S-2 diisopropylaminoethyl-methyl phosphonothiolate (VX) and the carbamate compound 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate (physostigmine) were studied on the metathoracic...
5.
Effectiveness of physostigmine as a pretreatment drug for protection of rats from organophosphate poisoning
Deshpande S, Viana G, Kauffman F, Rickett D, Albuquerque E
Fundam Appl Toxicol . 1986 Apr; 6(3):566-77. PMID: 3699340
The effectiveness of physostigmine and atropine pretreatment against the lethal effects of sarin was studied in rats given lethal subcutaneous injections (130 micrograms/kg) of the organophosphate. Pretreatment of these animals...
6.
Central respiratory effects versus neuromuscular actions of nerve agents
Rickett D, Glenn J, Beers E
Neurotoxicology . 1986 Jan; 7(1):225-36. PMID: 3714123
The relative contributions of peripheral neuromuscular and central nervous system components in the respiratory failure following acute exposure to organophosphorous anticholinesterase (AChE) agents remain unclear. We examined the effects of...
7.
Multiple actions of anticholinesterase agents on chemosensitive synapses: molecular basis for prophylaxis and treatment of organophosphate poisoning
Albuquerque E, Deshpande S, Kawabuchi M, Aracava Y, IDRISS M, Rickett D, et al.
Fundam Appl Toxicol . 1985 Dec; 5(6 Pt 2):S182-203. PMID: 2868960
The present study demonstrates that the reversible and irreversible anti-ChE agents have direct actions on the nicotinic acetylcholine receptor-ionic channel (AChR) and on the locust glutamatergic neuromuscular junction. In addition,...
8.
The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex
Shaw K, Aracava Y, Akaike A, Daly J, Rickett D, Albuquerque E
Mol Pharmacol . 1985 Dec; 28(6):527-38. PMID: 2417099
The actions of the carbamate cholinesterase inhibitors, physostigmine (Phy) and physostigmine methiodide (MetPhy), were studied on the acetylcholine receptor-ion channel complex (AChR) of skeletal muscles. Low concentrations of these agents...
9.
The interaction of anticholinesterase agents with the acetylcholine receptor-ionic channel complex
Albuquerque E, Akaike A, Shaw K, Rickett D
Fundam Appl Toxicol . 1984 Apr; 4(2 Pt 2):S27-33. PMID: 6327444
The actions of pyridostigmine (Pyr), a quaternary carbamate compound, and physostigmine ( Phy ), a tertiary carbamate, both known for their reversible inhibition of acetylcholinesterase (AChE), were studied on the...
10.
The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing, and binding properties
Pascuzzo G, Akaike A, Maleque M, Shaw K, Aronstam R, Rickett D, et al.
Mol Pharmacol . 1984 Jan; 25(1):92-101. PMID: 6323955
The actions of pyridostigmine (Pyr), an anticholinesterase agent, were studied on the acetylcholine (ACh) receptor-ion channel complex and on the electrically excitable membrane of the frog cutaneous pectoris and sartorius...