D L Nagle
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Explore the profile of D L Nagle including associated specialties, affiliations and a list of published articles.
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18
Citations
584
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Recent Articles
1.
Moore K, Nagle D
Annu Rev Genet
. 2000 Nov;
34:653-686.
PMID: 11092842
In 1990, David Baltimore predicted that the 1990s would be the decade of the mouse (). This certainly proved to be true: The mouse has contributed immensely to biological research...
2.
Nagle D, McGrail S, Vitale J, Woolf E, Dussault Jr B, DiRocco L, et al.
Nature
. 1999 Mar;
398(6723):148-52.
PMID: 10086355
Genetic studies have shown that mutations within the mahogany locus suppress the pleiotropic phenotypes, including obesity, of the agouti-lethal-yellow mutant. Here we identify the mahogany gene and its product; this...
3.
Hunter J, Shao J, Smutko J, Dussault B, Nagle D, Woolf E, et al.
Genomics
. 1998 Nov;
54(1):116-23.
PMID: 9806836
We recently described a novel gene, melastatin, whose expression is inversely correlated with melanoma aggressiveness. Chromosomal localization of this gene places it on mouse chromosome 7 and in the 15q13-q14...
4.
Yager L, Lee H, Nagle D, Zimmerman J
Genetics
. 1998 Aug;
149(4):1777-86.
PMID: 9691036
Conidiation in Aspergillus nidulans is induced by exposure to red light but can also be induced by blue light in certain mutant strains. We have isolated a mutation in the...
5.
Markel P, Shu P, Ebeling C, Carlson G, Nagle D, Smutko J, et al.
Nat Genet
. 1997 Nov;
17(3):280-4.
PMID: 9354790
Congenic breeding strategies are becoming increasingly important as a greater number of complex trait linkages are identified. Traditionally, the development of a congenic strain has been a time-consuming endeavour, requiring...
6.
Karim M, Nagle D, Kandil H, Burger J, Moore K, Spritz R
Hum Mol Genet
. 1997 Jul;
6(7):1087-9.
PMID: 9215679
Chediak-Higashi syndrome (CHS) is a rare, usually fatal, autosomal recessive disorder characterized by severe immunologic defects, reduced pigmentation, progressive neurologic dysfunction and a bleeding diathesis. The hallmark of CHS is...
7.
Misumi D, Nagle D, McGrail S, Dussault Jr B, Smutko J, Chen H, et al.
Genomics
. 1997 Feb;
40(1):147-50.
PMID: 9070932
During the recent cloning of the mouse Lyst gene we developed both a high-resolution genetic map and a complete YAC and BAC contig of the Lyst critical region on mouse...
8.
Zimmerman J, Bui Q, Steingrimsson E, Nagle D, Fu W, Genin A, et al.
Genome Res
. 1997 Feb;
7(2):128-41.
PMID: 9049631
The Drosophila eyes absent (eya) gene plays an essential role in the events that lead to proper development of the fly eye and embryo. Here we report the analysis of...
9.
Kluppel M, Nagle D, Bucan M, Bernstein A
Development
. 1997 Jan;
124(1):65-77.
PMID: 9006068
Mutations in the murine dominant white spotting (W) locus cause pleiotropic developmental defects that affect hematopoietic cells, melanocytes, germ cells and the interstitial cells of Cajal in the gut. W...
10.
Nagle D, Karim M, Woolf E, Holmgren L, Bork P, Misumi D, et al.
Nat Genet
. 1996 Nov;
14(3):307-11.
PMID: 8896560
Chediak-Higashi syndrome (CHS) is a rare, autosomal recessive disorder characterized by hypopigmentation, severe immunologic deficiency with neutropenia and lack of natural killer (NK) cells, a bleeding tendency and neurologic abnormalities....