D Kent Arrell
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Explore the profile of D Kent Arrell including associated specialties, affiliations and a list of published articles.
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26
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1147
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Recent Articles
1.
Garmany A, Arrell D, Yamada S, Jeon R, Behfar A, Park S, et al.
Stem Cells Transl Med
. 2024 Sep;
13(11):1144-1159.
PMID: 39259666
Cardiopoiesis-primed human stem cells exert sustained benefit in treating heart failure despite limited retention following myocardial delivery. To assess potential paracrine contribution, the secretome of cardiopoiesis conditioned versus naïve human...
2.
Livia C, Inglis S, Crespo-Diaz R, Rizzo S, Mahlberg R, Bagwell M, et al.
J Am Heart Assoc
. 2024 May;
13(9):e032172.
PMID: 38700022
Background: The purpose of this study was to investigate a therapeutic approach targeting the inflammatory response and consequent remodeling from ischemic myocardial injury. Methods And Results: Coronary thrombus aspirates were...
3.
Arrell D, Park S, Yamada S, Alekseev A, Garmany A, Jeon R, et al.
Sci Rep
. 2022 May;
12(1):7314.
PMID: 35513538
Plasmalemmal ATP sensitive potassium (K) channels are recognized metabolic sensors, yet their cellular reach is less well understood. Here, transgenic Kir6.2 null hearts devoid of the K channel pore underwent...
4.
Arrell D, Crespo-Diaz R, Yamada S, Jeon R, Garmany A, Park S, et al.
Stem Cells Transl Med
. 2021 May;
10(9):1320-1328.
PMID: 34047493
Stem cell paracrine activity is implicated in cardiac repair. Linkage between secretome functionality and therapeutic outcome was here interrogated by systems analytics of biobanked human cardiopoietic cells, a regenerative biologic...
5.
Arrell D, Rosenow C, Yamada S, Behfar A, Terzic A
NPJ Regen Med
. 2020 Mar;
5:5.
PMID: 32194990
Cardiopoietic stem cells have reached advanced clinical testing for ischemic heart failure. To profile their molecular influence on recipient hearts, systems proteomics was here applied in a chronic model of...
6.
Yamada S, Arrell D, Rosenow C, Bartunek J, Behfar A, Terzic A
Stem Cells Transl Med
. 2019 Aug;
9(1):74-79.
PMID: 31373782
Response to stem cell therapy in heart failure is heterogeneous, warranting a better understanding of outcome predictors. This study assessed left ventricular volume, a surrogate of disease severity, on cell...
7.
Park S, Arrell D, Reyes S, Park E, Terzic A
Sci Rep
. 2017 Nov;
7(1):14499.
PMID: 29101331
Growth factors are signaling molecules which orchestrate cell growth, proliferation and differentiation. The majority are secreted proteins, exported through the classical endoplasmic reticulum (ER)/Golgi-dependent pathway, but a few are released...
8.
Lindsey M, Mayr M, Gomes A, Delles C, Arrell D, Murphy A, et al.
Circulation
. 2015 Jul;
132(9):852-72.
PMID: 26195497
The year 2014 marked the 20th anniversary of the coining of the term proteomics. The purpose of this scientific statement is to summarize advances over this period that have catalyzed...
9.
Yamada S, Arrell D, Martinez-Fernandez A, Behfar A, Kane G, Perez-Terzic C, et al.
J Am Heart Assoc
. 2015 May;
4(5).
PMID: 25964205
Background: Cardiac resynchronization therapy using bi-ventricular pacing is proven effective in the management of heart failure (HF) with a wide QRS-complex. In the absence of QRS prolongation, however, device-based resynchronization...
10.