D J Surmeier
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Explore the profile of D J Surmeier including associated specialties, affiliations and a list of published articles.
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84
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4050
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Recent Articles
11.
Rick C, Ebert A, Virag T, Bohn M, Surmeier D
Dev Neurosci
. 2006 Oct;
28(6):528-37.
PMID: 17028430
The cell line MN9D, a fusion of embryonic ventral mesencephalic and neuroblastoma cells, is extensively used as a model of dopamine (DA) neurons because it expresses tyrosine hydroxylase and synthesizes...
12.
Guan D, Lee J, Tkatch T, Surmeier D, Armstrong W, Foehring R
J Physiol
. 2005 Dec;
571(Pt 2):371-89.
PMID: 16373387
Potassium channels are extremely diverse regulators of neuronal excitability. As part of an investigation into how this molecular diversity is utilized by neurones, we examined the expression and biophysical properties...
13.
Rakhilin S, Olson P, Nishi A, Starkova N, Fienberg A, Nairn A, et al.
Science
. 2004 Oct;
306(5696):698-701.
PMID: 15499021
Calmodulin (CaM) is a major effector for the intracellular actions of Ca2+ in nearly all cell types. We identified a CaM-binding protein, designated regulator of calmodulin signaling (RCS). G protein-coupled...
14.
Vergara R, Rick C, Hernandez-Lopez S, Laville J, Guzman J, Galarraga E, et al.
J Physiol
. 2003 Sep;
553(Pt 1):169-82.
PMID: 12963790
In a rat corticostriatal slice, brief, suprathreshold, repetitive cortical stimulation evoked long-lasting plateau potentials in neostriatal neurons. Plateau potentials were often followed by spontaneous voltage transitions between two preferred membrane...
15.
Yan Z, Flores-Hernandez J, Surmeier D
Neuroscience
. 2001 Apr;
103(4):1017-24.
PMID: 11301208
The postsynaptic effects of acetylcholine in the striatum are largely mediated by muscarinic receptors. Two of the five cloned muscarinic receptors (M1 and M4) are expressed at high levels by...
16.
Maurice N, Tkatch T, Meisler M, Sprunger L, Surmeier D
J Neurosci
. 2001 Mar;
21(7):2268-77.
PMID: 11264302
Dopamine (DA) is a well established modulator of prefrontal cortex (PFC) function, yet the cellular mechanisms by which DA exerts its effects in this region are controversial. A major point...
17.
Foehring R, Mermelstein P, Song W, Ulrich S, Surmeier D
J Neurophysiol
. 2000 Nov;
84(5):2225-36.
PMID: 11067968
Whole cell recordings from acutely dissociated neocortical pyramidal neurons and striatal medium spiny neurons exhibited a calcium-channel current resistant to known blockers of L-, N-, and P/Q-type Ca(2+) channels. These...
18.
Flores-Hernandez J, Hernandez S, Snyder G, Yan Z, Fienberg A, Moss S, et al.
J Neurophysiol
. 2000 May;
83(5):2996-3004.
PMID: 10805695
Dopamine is a critical determinant of neostriatal function, but its impact on intrastriatal GABAergic signaling is poorly understood. The role of D(1) dopamine receptors in the regulation of postsynaptic GABA(A)...
19.
Song W, Tkatch T, Surmeier D
J Neurophysiol
. 2000 Jan;
83(1):322-32.
PMID: 10634875
Adenosine is a potent regulator of acetylcholine release in the striatum, yet the mechanisms mediating this regulation are largely undefined. To begin to fill this gap, adenosine receptor expression and...
20.
Tkatch T, Baranauskas G, Surmeier D
J Neurosci
. 2000 Jan;
20(2):579-88.
PMID: 10632587
A-type K(+) currents are key determinants of repetitive activity and synaptic integration. Although several gene families have been shown to code for A-type channel subunits, recent studies have suggested that...