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D J Mahad

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Articles 8
Citations 107
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Recent Articles
1.
Campbell G, Reeve A, Ziabreva I, Polvikoski T, Taylor R, Reynolds R, et al.
Neuropathol Appl Neurobiol . 2012 Jul; 39(4):377-89. PMID: 22762368
Aims: Although mitochondrial abnormalities have been reported within paraspinal muscles in patients with axial weakness and neuromuscular disease as well as with ageing, the basis of respiratory deficiency in paraspinal...
2.
Zambonin J, Engeham S, Campbell G, Ziabreva I, Beadle N, Taylor R, et al.
J Neurosci Methods . 2010 Jul; 192(1):115-20. PMID: 20659500
Mitochondrial defects have been implicated in the degeneration of axons in a number of CNS disorders, including multiple sclerosis. Uniquely, mitochondria harbor the only non-nuclear DNA (mitochondrial DNA or mtDNA),...
3.
Mahad D, Ziabreva I, Campbell G, Laulund F, Murphy J, Reeve A, et al.
J Neurosci Methods . 2009 Sep; 184(2):310-9. PMID: 19723540
Cytochrome c oxidase or mitochondrial respiratory chain complex IV is where over 90% of oxygen is consumed. The relationship between complex IV activity and mitochondrial proteins, which provides a guide...
4.
Jaros E, Mahad D, Hudson G, Birchall D, Sawcer S, Griffiths P, et al.
Neurology . 2007 Jul; 69(2):214-6. PMID: 17620555
No abstract available.
5.
Mahad D, Mahad D, Hellden A, Jarvis J, Mitra D, Gholkar A, et al.
J Neurol Neurosurg Psychiatry . 2005 Aug; 76(9):1308-9. PMID: 16107379
No abstract available.
6.
Mahad D, Lawry J, Howell S, Woodroofe M
Mult Scler . 2003 Apr; 9(2):189-98. PMID: 12708814
The interaction between chemokines and their receptors leads to selective recruitment of cells to foci of inflammation. Cross-sectional studies have reported significantly different expression of chemokine receptors CXCR3, CCR5 and...
7.
Mahad D, Howell S, Woodroofe M
J Neurol Neurosurg Psychiatry . 2002 Aug; 73(3):320-3. PMID: 12185171
Chemokines are likely to contribute to the pathogenesis of chronic inflammatory demyelinating polyneuropathy (CIDP), as evidenced by data from experimental autoimmune neuritis. The alpha and beta chemokines in the cerebrospinal...
8.
Mahad D, Howell S, Woodroofe M
J Neurol Neurosurg Psychiatry . 2002 Mar; 72(4):498-502. PMID: 11909910
Objective: To define the chemokine profile in the CSF of patients with multiple sclerosis (MS) and compare it with three control groups; patients with benign headache (headache), non-inflammatory neurological diseases...