D J Blackbourn
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Explore the profile of D J Blackbourn including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
662
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Recent Articles
1.
Butler L, Jeffery H, Wheat R, Long H, Rae P, Nash G, et al.
J Virol
. 2012 Apr;
86(13):7158-66.
PMID: 22532676
Endothelial cells (EC) can present antigen to either CD8(+) T lymphocytes through constitutively expressed major histocompatibility complex class I (MHC-I) or CD4(+) T lymphocytes through gamma interferon (IFN-γ)-induced MHC-II. Kaposi's...
2.
Mutocheluh M, Hindle L, Areste C, Chanas S, Butler L, Lowry K, et al.
J Gen Virol
. 2011 Jun;
92(Pt 10):2394-2398.
PMID: 21697347
Kaposi's sarcoma-associated herpesvirus (KSHV) encodes four viral interferon regulatory factors (vIRF-1-4). We investigated the mechanism and consequences of vIRF-2-mediated inhibition of interferon-response element signalling following type I interferon (IFN) induction....
3.
Butler L, Jeffery H, Wheat R, Rae P, Townsend K, Alkharsah K, et al.
J Virol
. 2011 May;
85(14):7321-32.
PMID: 21543487
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS), an endothelial cell (EC) neoplasm characterized by dysregulated angiogenesis and inflammation. KSHV infection of EC causes production of...
4.
Spiller O, Mark L, Blue C, Proctor D, Aitken J, Blom A, et al.
J Virol
. 2006 Mar;
80(8):4068-78.
PMID: 16571823
Complement, which bridges innate and adaptive immune responses as well as humoral and cell-mediated immunity, is antiviral. Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a lytic cycle protein called KSHV complement control...
5.
Locher C, Sykes K, Blackbourn D, Johnston S
J Med Primatol
. 2003 Jan;
31(6):323-9.
PMID: 12519210
Immunization using genetic expression libraries may be an improvement over conventional DNA immunization using a single gene because more epitopes are simultaneously presented to the immune system. In this study,...
6.
Blackbourn D, Lennette E, Klencke B, Moses A, Chandran B, Weinstein M, et al.
AIDS
. 2000 Jul;
14(9):1123-33.
PMID: 10894276
Design: A selection of primary and transformed cell types were evaluated for their susceptibility to infection with human herpesvirus 8 (HHV-8)/Kaposi's sarcoma-associated herpesvirus. Methods: Sources of HHV-8 included Kaposi's sarcoma...
7.
Blackbourn D, Fujimura S, Kutzkey T, Levy J
AIDS
. 2000 Mar;
14(1):98-9.
PMID: 10714578
No abstract available.
8.
Locher C, Blackbourn D, Levy J
Immunol Lett
. 1999 Apr;
66(1-3):151-7.
PMID: 10203048
Human immunodeficiency virus type 2 (HIV-2)-infected baboons (Papio cynocephalus) provide a valuable animal model for the study of acquired immunodefidency syndrome (AIDS) pathogenesis since many features of disease progression resemble...
9.
Blackbourn D, Osmond D, Levy J, Lennette E
J Infect Dis
. 1998 Dec;
179(1):237-9.
PMID: 9841846
The objective of this study was to evaluate the behavioral risks that are associated with human herpesvirus 8 (HHV-8) infection in a cohort of young homosexual men. Seventy-nine subjects (ages...
10.
Locher C, Barnett S, Herndier B, Blackbourn D, Reyes-Teran G, Murthy K, et al.
Arch Pathol Lab Med
. 1998 Jun;
122(6):523-33.
PMID: 9625420
Objective: To assess disease progression in baboons (Papio cynocephalus) that were infected with two human immunodeficiency virus-2 (HIV-2) isolates. Methods: Eight baboons were inoculated intravenously with either HIV-2UC2 or HIV-2UC14...