D E McCall
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Explore the profile of D E McCall including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
234
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Recent Articles
1.
Wong P, Quan M, Saye J, Bernard R, Crain Jr E, McCall D, et al.
J Cardiovasc Pharmacol
. 1995 Sep;
26(3):354-62.
PMID: 8583775
The angiotensin II (Ang II) type 1 receptor (AT1) mediates all known physiological effects of ANG II, whereas functions of the type 2 (AT2) receptor are not clear. Should undesirable...
2.
VanAtten M, Ensinger C, Chiu A, McCall D, Nguyen T, Wexler R, et al.
J Med Chem
. 1993 Dec;
36(25):3985-92.
PMID: 8258820
The availability of peptide and non-peptide Ang II receptor antagonists has permitted the study of Ang II receptor heterogeneity. It is now widely recognized that there are at least two...
3.
Wong P, Aldrich P, Chiu A, Earl R, Hart S, Johnson A, et al.
J Pharmacol Exp Ther
. 1993 Jun;
265(3):1088-95.
PMID: 8099616
2-Amino-1,4-dihydro-4-(2-[-4[4-(2-methoxyphenyl)-1-piperazinyl]- butylsulfinyl]phenyl)-6-methyl-5-nitro-3-pyridine carboxylic acid methyl ester (XB513) was designed to combine the calcium agonistic and alpha-1 adrenergic receptor antagonistic properties in the same molecule. It inhibited the specific binding of...
4.
Chiu A, Dunscomb J, McCall D, Benfield P, Baubonis W, Sauer B
Regul Pept
. 1993 Mar;
44(2):141-7.
PMID: 8469769
The objective of this study was to determine whether the binding signature of the cloned rat AT1A receptor transfected into Chinese hamster ovary cells could be distinguished from that of...
5.
Chiu A, McCall D, Roscoe W
Biochem Biophys Res Commun
. 1992 Nov;
188(3):1030-9.
PMID: 1445340
[125I]EXP985 is the first nonpeptide radioligand with high specific activity for the AT1 angiotensin receptor. The biochemical and pharmacological profiles of this ligand were determined using either ligand-receptor binding techniques...
6.
Chiu A, Carini D, Duncia J, Leung K, McCall D, PRICE Jr W, et al.
Biochem Biophys Res Commun
. 1991 May;
177(1):209-17.
PMID: 2043107
DuP 532 is a novel nonpeptide angiotensin II (AII) receptor antagonist under development for the treatment of hypertension. DuP 532 is a more potent antihypertensive agent in renal hypertensive rats...
7.
Chiu A, McCall D, PRICE Jr W, Wong P, Carini D, Duncia J, et al.
Am J Hypertens
. 1991 Apr;
4(4 Pt 2):282S-287S.
PMID: 1854453
DuP 753, 2-n-butyl-4-chloro-5-hydroxymethyl-1-[2'-(1H-tetrazol-5-yl) biphenyl-4-yl)methyl]imidazole, potassium salt, was characterized in vitro with respect to its affinity and specificity for functional antagonism of angiotensin II (AII) receptors. In rat adrenal cortical microsomes...
8.
Herblin W, Chiu A, McCall D, Ardecky R, Carini D, Duncia J, et al.
Am J Hypertens
. 1991 Apr;
4(4 Pt 2):299S-302S.
PMID: 1854455
The possibility of receptor heterogeneity in the angiotensin II (AII) system has been suggested previously, based on differences in Kd values or sensitivity to thiol reagents. One of our earliest...
9.
Chiu A, Roscoe W, McCall D, Timmermans P
Receptor
. 1991 Jan;
1(3):133-40.
PMID: 1843203
The receptor subtypes that mediate the vasoconstrictor and hypertrophic responses of AII were evaluated in cultured aortic smooth muscle cells from rat. The AII receptors were characterized by means of...
10.
Chiu A, McCall D, Aldrich P, Timmermans P
Biochem Biophys Res Commun
. 1990 Nov;
172(3):1195-202.
PMID: 2244903
[3H]Dup 753, a nonpeptide angiotensin II (AII) receptor antagonist radioligand, was used to characterize a subtype of AII receptors in rat adrenal cortical microsomes. By Scatchard analysis, a single class...