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D E Elder

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Articles 121
Citations 2875
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Recent Articles
11.
Spatz A, Cook M, Elder D, Piepkorn M, Ruiter D, Barnhill R
Eur J Cancer . 2003 Aug; 39(13):1861-5. PMID: 12932663
In the recently revised melanoma staging system proposed by the American Joint Committee on Cancer (AJCC), ulceration assessment by the pathologist is a pivotal parameter. Patients upstaged because of ulceration...
12.
Satyamoorthy K, Li G, Van Belle P, Elder D, Herlyn M
Melanoma Res . 2002 Oct; 12(5):449-52. PMID: 12394186
Melanin pigments often co-purify during preparation of nucleic acids from cells or tissues of melanocytic origin. Contaminating melanin can severely impede subsequent analyses of RNA. We attempted to eliminate melanin...
13.
Goldstein A, Chidambaram A, Halpern A, Holly E, Guerry IV D, Sagebiel R, et al.
Melanoma Res . 2002 Feb; 12(1):51-5. PMID: 11828258
To date, two genes have been implicated in melanoma pathogenesis. The first, CDKN2A, is a tumour suppressor gene with germline mutations detected in 20% of melanoma-prone families. The second, CDK4,...
14.
Wildemore 4th J, Schuchter L, Mick R, Synnestvedt M, Elenitsas R, Bedrosian I, et al.
Ann Plast Surg . 2001 May; 46(5):488-94. PMID: 11352421
Despite improvements in the identification and treatment of melanoma, local recurrence continues to challenge the success of current melanoma therapy. A retrospective analysis of 1,996 patients presenting from 1990 to...
15.
Darlow B, Winterbourn C, Inder T, Graham P, Harding J, Weston P, et al.
J Pediatr . 2001 Feb; 136(4):473-80. PMID: 10753245
Background: Low selenium (SE) status has been documented in preterm infants and has been suggested to be a risk factor for chronic lung disease. Methods: A total of 534 infants...
16.
Christos P, Oliveria S, Berwick M, Guerry D4th , Elder D, Synnestvedt M, et al.
J Clin Epidemiol . 2000 Oct; 53(10):1044-53. PMID: 11027938
We conducted a descriptive study to assess the relationship between increasing age and the reporting of melanoma signs/symptoms in 634 hospital-based and 624 population-based incident cases of melanoma. Multivariate logistic...
17.
Bedrosian I, Faries M, Guerry 4th D, Elenitsas R, Schuchter L, Mick R, et al.
Ann Surg Oncol . 2000 May; 7(4):262-7. PMID: 10819365
Background: Patients with thin primary melanomas (< or = 1 mm) generally have an excellent prognosis. However, the presence of a vertical growth phase (VGP) adversely impacts the survival rate....
18.
Hsu M, Meier F, Nesbit M, Hsu J, van Belle P, Elder D, et al.
Am J Pathol . 2000 May; 156(5):1515-25. PMID: 10793063
In human epidermis, functional symbiosis requires homeostatic balance between keratinocytes and melanocytes. Compelling evidence from co-culture studies demonstrated a sophisticated, multileveled regulation of normal melanocytic phenotype orchestrated by undifferentiated, basal-type...
19.
Lyle S, Christofidou-Solomidou M, Liu Y, Elder D, Albelda S, Cotsarelis G
J Investig Dermatol Symp Proc . 2000 Feb; 4(3):296-301. PMID: 10674385
Stem cells are vital for the homeostasis of self-renewing tissues and their manipulation may have wide ranging applications, including gene therapy, wound repair, and tissue transplantation. Although rodent hair follicle...
20.
Lyle S, Salhany K, Elder D
Mod Pathol . 2000 Feb; 13(1):52-5. PMID: 10658910
Tumor-infiltrating lymphocytes (TIL) have been shown to be an independent prognostic factor in melanomas. To better characterize the host immune response, we have classified TIL by their immunoreactivity against lymphoid...