D D Koblin
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Explore the profile of D D Koblin including associated specialties, affiliations and a list of published articles.
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82
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Recent Articles
1.
Eger 2nd E, Halsey M, Koblin D, Laster M, IONESCU P, Konigsberger K, et al.
Anesth Analg
. 2001 Sep;
93(4):922-7.
PMID: 11574358
Unlabelled: The differences in potencies of optical isomers of anesthetics support the hypothesis that anesthetics act by specific receptor interactions. Diastereoisomerism and geometrical isomerism offer further tests of this hypothesis...
2.
Eger 2nd E, Halsey M, Harris R, Koblin D, Pohorille A, Sewell J, et al.
Anesth Analg
. 1999 Jun;
88(6):1395-400.
PMID: 10357351
Unlabelled: All series of volatile and gaseous compounds contain members that can produce anesthesia, as defined by the minimum alveolar anesthetic concentration (MAC) required to produce immobility in response to...
3.
Koblin D, Laster M, IONESCU P, Gong D, Eger 2nd E, Halsey M, et al.
Anesth Analg
. 1999 May;
88(5):1161-7.
PMID: 10320188
Unlabelled: The several potent inhaled anesthetics released for clinical use in the past four decades have been halogenated ethers, and, with one exception, methyl ethyl ethers. In the present report,...
4.
Eger 2nd E, Koblin D, Sonner J, Gong D, Laster M, IONESCU P, et al.
Anesth Analg
. 1999 Apr;
88(4):884-92.
PMID: 10195542
Unlabelled: Some inhaled compounds cause convulsions. To better appreciate the physical basis for this property, we correlated the partial pressures that produced convulsions in rats with the lipophilicity (nonpolarity) and...
5.
Koblin D, Fang Z, Eger 2nd E, Laster M, Gong D, IONESCU P, et al.
Anesth Analg
. 1998 Aug;
87(2):419-24.
PMID: 9706943
Unlabelled: We assessed the anesthetic properties of helium and neon at hyperbaric pressures by testing their capacity to decrease anesthetic requirement for desflurane using electrical stimulation of the tail as...
6.
Trudell J, Koblin D, Eger 2nd E
Anesth Analg
. 1998 Aug;
87(2):411-8.
PMID: 9706942
Unlabelled: How some noble and diatomic gases produce anesthesia remains unknown. Although these gases have apparently minimal capacities to interact with a putative anesthetic site, xenon is a clinical anesthetic,...
7.
Yost C, Hampson A, Leonoudakis D, Koblin D, Bornheim L, Gray A
Anesth Analg
. 1998 Jun;
86(6):1294-300.
PMID: 9620523
Unlabelled: A naturally occurring brain lipid, cis-9,10-octadeceamide--oleamide (OA), is found in increased concentrations in the cerebrospinal fluid of sleep-deprived cats, which suggests that it may be an endogenous sleep-inducing substance....
8.
Eger 2nd E, Gong D, Koblin D, Bowland T, IONESCU P, Laster M, et al.
Anesth Analg
. 1998 Feb;
86(2):414-21.
PMID: 9459259
Unlabelled: This study documents the differences in kinetics of 2 h (n = 7) and 4 h (n = 9) of 1.25 minimum alveolar anesthetic concentration (MAC) of desflurane (9.0%)...
9.
Griffiths R, IONESCU P, Fang Z, Koblin D, EGER E
Br J Anaesth
. 1997 Dec;
79(3):389-91.
PMID: 9389863
Enhancement of choline acetyltransferase (ChAT) activity and increased intraneuronal acetylcholine (ACh) may explain the convulsant activity of some inhaled compounds. Enflurane, for example, enhances such activity. Accordingly, we measured choline...
10.
Eger 2nd E, Gong D, Koblin D, Bowland T, IONESCU P, Laster M, et al.
Anesth Analg
. 1997 Nov;
85(5):1154-63.
PMID: 9356118
Unlabelled: Sevoflurane (CH2F-O-CH[CF3]2) reacts with carbon dioxide absorbents to produce Compound A (CH2F-O-C[=CF2][CF3]). Because of concern about the potential nephrotoxicity of Compound A, the United States package label (but not...