D D Breimer
Overview
Explore the profile of D D Breimer including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
361
Citations
3678
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
de Leede L, De Boer A, Havermans J, Breimer D
Pharm Res
. 2013 Nov;
1(4):164-8.
PMID: 24277285
The extent of "first-pass" elimination of racemic propranolol and dextropropranolol in doses of 0.25 or 0.50 mg was investigated in relation to the site of drug administration in the rectum...
2.
de Leede L, De Boer A, Feijen C, Breimer D
Pharm Res
. 2013 Nov;
1(3):129-34.
PMID: 24277250
Lidocaine was administered to healthy volunteers at different sites in the rectum. Unchanged drug and monoethylglycinexylidide (MEGX) concentrations were measured in plasma with a newly developed gas chromatographic method. Lidocaine...
3.
Teunissen M, Brorens I, De Langen H, Geerlings A, Breimer D
Pharm Res
. 2013 Nov;
3(3):156-61.
PMID: 24271521
Two model substrates for oxidative hepatic enzyme activity, viz. antipyrine (A) and theophylline (T), were given simultaneously to rats by iv administration. Blood concentrations of A and T were measured...
4.
van Bladeren P, Breimer D, van Huijgevoort J, Vermeulen N, van der Gen A
Biochem Pharmacol
. 2010 Nov;
30(17):2499-502.
PMID: 21043256
No abstract available.
5.
van der Sandt I, Gaillard P, Voorwinden H, De Boer A, Breimer D
Pharm Res
. 2001 Jul;
18(5):587-92.
PMID: 11465412
Purpose: To investigate whether P-glycoprotein (Pgp) protects the in vitro BBB against the cytotoxic effects of anti-tumour drugs. Methods: In an in vitro BBB coculture model the influence of the...
6.
van der Sandt I, Smolders R, Nabulsi L, Zuideveld K, De Boer A, Breimer D
Eur J Pharm Sci
. 2001 Jul;
14(1):81-6.
PMID: 11457654
The role of P-glycoprotein on the efflux of the 5-HT(1A) receptor agonist flesinoxan across the blood-brain barrier in vivo and in vitro was investigated. In vitro, the transport ratios (representing...
7.
Gaillard P, van der Meide P, De Boer A, Breimer D
Neuroreport
. 2001 Jul;
12(10):2189-93.
PMID: 11447332
The pharmacological effect of glucocorticoids and type 1 interferons (IFNs), simultaneously used as therapeuticals for multiple sclerosis (MS), on the (inflamed) blood-brain barrier (BBB) was investigated in vitro. Although both...
8.
van der Sandt I, Vos C, Nabulsi L, Voorwinden H, De Boer A, Breimer D
AIDS
. 2001 Mar;
15(4):483-91.
PMID: 11242145
Objective: To investigate the involvement of P-glycoprotein (Pgp) and the multidrug resistance-associated protein (MRP) on the active transport of the HIV protease inhibitors amprenavir, ritonavir and indinavir. Methods: The transport...
9.
Breimer D
Eur J Pharm Sci
. 2001 Mar;
12(4):347-52.
PMID: 11231100
The markets for the traditional output of schools of pharmacy, namely education, research and graduates, are changing. The main private client in these markets, the pharmaceutical industry, is moving fast...
10.
Gaillard P, van der Sandt I, Voorwinden L, Vu D, Nielsen J, De Boer A, et al.
Pharm Res
. 2001 Jan;
17(10):1198-205.
PMID: 11145224
Purpose: To investigate the influence of astrocytes on P-glycoprotein (Pgp) expression and intracellular accumulation of Pgp substrates, separate from their net transcellular transport across the blood-brain barrier (BBB). Methods: An...