D C Lye
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Explore the profile of D C Lye including associated specialties, affiliations and a list of published articles.
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19
Citations
306
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Recent Articles
1.
Wee L, Yap A, Dickens B, Tan S, Ong B, Lye D, et al.
Public Health
. 2024 Jun;
233:38-44.
PMID: 38850601
Objectives: Socio-economic status (SES) disparities exist in the uptake of COVID-19 vaccination; however, most studies were conducted during the initial pandemic wave when vaccination was less discretionary, limiting generalizability. We...
2.
Henderson A, Paterson D, Chatfield M, Tambyah P, Lye D, De P, et al.
Clin Infect Dis
. 2020 Oct;
73(11):e3842-e3850.
PMID: 33106863
Introduction: This study aims to assess the association of piperacillin/tazobactam and meropenem minimum inhibitory concentration (MIC) and beta-lactam resistance genes with mortality in the MERINO trial. Methods: Blood culture isolates...
3.
Tay H, Chow A, Ng T, Lye D
Sci Rep
. 2019 Sep;
9(1):13440.
PMID: 31530847
Severe Clostridioides difficile infection (CDI) is associated with poorer outcomes. We aimed to identify risk factors and treatment outcomes of severe CDI. This was a retrospective cohort study. Eligible patients...
4.
Harris P, McNamara J, Lye D, Davis J, Bernard L, Cheng A, et al.
Clin Microbiol Infect
. 2016 Nov;
23(8):533-541.
PMID: 27810466
Objectives: To define standardized endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infections (BSI). Methods: Prospective studies, randomized trials or registered protocols comparing antibiotic therapies...
5.
Chow A, Ang A, Chow C, Ng T, Teng C, Ling L, et al.
Int J Antimicrob Agents
. 2016 Jan;
47(2):132-9.
PMID: 26774157
Antimicrobial stewardship is used to combat antimicrobial resistance. In Singapore, a tertiary hospital has integrated a computerised decision support system, called Antibiotic Resistance Utilisation and Surveillance-Control (ARUSC), into the electronic...
6.
Hwang J, Chow A, Lye D, Wong C
Epidemiol Infect
. 2016 Jan;
144(9):1999-2005.
PMID: 26758244
The Charlson comorbidity index (CCI) is widely used for control of confounding from comorbidities in epidemiological studies. International Classification of Diseases (ICD)-coded diagnoses from administrative hospital databases is potentially an...
7.
Yeo Q, Lye D, Sathappan Ss S
Med J Malaysia
. 2015 Jun;
70(1):54-6.
PMID: 26032534
Intra-articular therapies, such as steroid injection, viscosupplement injection and acupuncture, are common non-surgical options for patients with osteoarthritis of the knee. With any intra-articular injection or acupuncture procedure, there is...
8.
Tang S, Lye D, Jureen R, Sng L, Hsu L
Clin Microbiol Infect
. 2015 Feb;
21(3):236-41.
PMID: 25658536
Nontuberculous mycobacteria infection is a growing global concern, but data from Asia are limited. This study aimed to describe the distribution and antibiotic susceptibility profiles of rapidly growing mycobacterium (RGM)...
9.
Wong C, Lye D, Lee C, Leo Y
Singapore Med J
. 2011 Dec;
52(12):860-3.
PMID: 22159926
Introduction: The incidence of human immunodeficiency virus (HIV) infection in Singapore is on the rise. We aimed to study the clinical epidemiology of acute HIV infection in Singapore. Methods: All...
10.
Lye D, Earnest A, Ling M, Lee T, Yong H, Fisher D, et al.
Clin Microbiol Infect
. 2011 Aug;
18(5):502-8.
PMID: 21851482
Multidrug-resistant Gram-negative bacteria (MDR-GNB) are an emerging public health threat. Accurate estimates of their clinical impact are vital for justifying interventions directed towards preventing or managing infections caused by these...