D C KVAM
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Explore the profile of D C KVAM including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
172
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Recent Articles
1.
Kehe C, Lasseter K, Miller N, Wick K, Shamblen E, Ekholm B, et al.
Ther Drug Monit
. 1992 Apr;
14(2):132-4.
PMID: 1585397
The inhalation of atropine sulfate from a pressurized metered-dose inhaler was investigated in a nonrandomized four-period rising-dose study. Eight healthy, nonsmoking subjects received 1.7, 3.4, and 5.2 mg of atropine...
2.
Holtzman J, Finley D, Mottonen L, Berry D, Ekholm B, KVAM D, et al.
Clin Pharmacol Ther
. 1989 Jul;
46(1):26-32.
PMID: 2501057
Flecainide and verapamil are antiarrhythmic agents that may be used in combination. We have examined their pharmacodynamic interaction by M-mode echocardiography and electrocardiography in eight normal male volunteers (24 +/-...
3.
Holtzman J, Weeks C, KVAM D, Berry D, Mottonen L, Ekholm B, et al.
Clin Pharmacol Ther
. 1989 Jul;
46(1):1-8.
PMID: 2501055
No abstract available.
4.
Welsh P, OConnell E, SACHS M, Moyer T, Wick K, Harrison L, et al.
Ann Allergy
. 1989 May;
62(5):396-400.
PMID: 2719348
Pharmacodynamic and pharmacokinetic properties of sustained-release anyhdrous theophylline (Theolair-SR) were similar when doses were given either immediately after or two hours after low-fat meals in children with moderate asthma requiring...
5.
Forland S, Cutler R, McQuinn R, KVAM D, Miller A, Conard G, et al.
J Clin Pharmacol
. 1988 Aug;
28(8):727-35.
PMID: 3145942
Study Objective: To determine the pharmacokinetics of oral flecainide acetate after single and multiple doses in patients with impaired renal function. Design: Paired study of single followed by multiple oral...
6.
Forland S, Burgess E, Blair A, Cutler R, KVAM D, Weeks C, et al.
J Clin Pharmacol
. 1988 Mar;
28(3):259-67.
PMID: 3129455
The pharmacokinetics of flecainide acetate were studied in 20 patients with varying degrees of renal impairment following a single oral dose. The patients were divided into two groups, on the...
7.
Holtzman J, KVAM D, Berry D, Mottonen L, Borrell G, Harrison L, et al.
Eur J Clin Pharmacol
. 1987 Jan;
33(1):97-9.
PMID: 3121353
No abstract available.
8.
Harrison L, Smallridge R, Lasseter K, Goldlust M, Shamblen E, Gam V, et al.
Am Rev Respir Dis
. 1986 Aug;
134(2):254-7.
PMID: 3740650
The inhalation of atropine sulfate was investigated in a randomized, 4-period, rising-dose study. Atropine sulfate 2, 4, and 6 mg by inhalation, and atropine free base 1.67 mg (equivalent to...
9.
Weeks C, Conard G, KVAM D, Fox J, Chang S, Paone R, et al.
J Clin Pharmacol
. 1986 Jan;
26(1):27-31.
PMID: 3950050
The possible effect of oral flecainide acetate on steady-state digoxin levels was assessed in 15 healthy men. Each volunteer received digoxin 0.25 mg daily (8 AM) for 22 consecutive days...
10.
Holtzman J, Berry D, KVAM D, Mottonen L, Borrell G
J Pharmacol Exp Ther
. 1984 Nov;
231(2):286-90.
PMID: 6491982
We have examined the analysis of pharmacodynamic data in normal subjects receiving propranolol, flecainide or the two together. We find that a second-order polynomial describes accurately the response of the...